[Dynamics of hepatobiliary system involvement in occupational COLD formation].

Study of 462 patients with occupational pulmonary diseases revealed that hepatobiliary diseases are among concomitants of occupational COLD. Inflammatory changes in gallbladder and bile ducts with bile dyskinesia are first manifestations of such diseases developing early at chronic nonobstructive bronchitis stage. Shortly, hepatosteatosis adds to these disorders.

[Allergic effects on the population of industrial air pollutants].

Increasing of the allergization of the population in industrial regions caused by chemical pollution of the air was noted. Some changes in respiratory tract and blood count were reported also.

[The rate of isolation of fungi in the genus Candida from the nasopharyngeal mucosa of the those in contact with the products from microbial protein manufacture].

In the mycological study of the air in working rooms at enterprises for the production of paprin and in the airspace of residential areas, as well as the study of the fungal contamination of the upper respiratory ways in workers and residents of the development zone, the isolation rate of the production fungal strains of the genus Candida from the nasopharynx was shown to depend on their content in the air. In the absence of producer microorganisms in the atmospheric air they were not detected among the population. The detection of yeast-like fungi of the genus Candida on the pharyngeal mucosa is of sanitary demonstrative importance for the evaluation of the specific microbial contamination of the air in working rooms and the air space of the development zone.

[Comparative evaluation of efficiency of various immunologic reactions with Candida antigens in detecting immediate hypersensitivity].

In the dynamic survey of 577 persons having had contacts with yeast-like fungi of the genus Candida the effectiveness of tests for the diagnosis of mycogenic sensitization was made with the use of a number of immunological methods. The basophil degranulation test was shown to have higher sensitivity and specificity in the detection of hypersensitivity to microbial strains used in the production processes of microbiological synthesis, while the use of polysaccharide antigens is more expedient in immunological reactions, such as the precipitation test with the finished product obtained by these processes and with C. albicans.

[Medico-biological criteria of the evaluation of air quality at the site of microbiological synthesis plants].

The efficacy of environmental protection in the areas of location of protein synthesis microbiologic plants was analyzed. It was established that under the conditions of observance of a technological regime and the stability of the gas cleaning systems for industrial affluents the operation of the plants caused no air pollution of residential districts by fungi producers and protein dust of the finished product. The study revealed the absence of detrimental health effect of microbiologic products.

[Use of immunomycologic indicators in solving the problems of health protection of pregnant workers in the microbial synthesis industry].

The study of 106 pregnant women engaged in microbiological synthesis production revealed the tendency to increasing genitalia contamination by Candida yeast-like fungi, including fungi-protein producers, and also oppression of immunologic reactivity in comparison with nonpregnant women and the control group. It was pointed out that from the beginning of their pregnancy period women should have no contact with yeast-like fungi.