Cry toxins, produced by the bacterium , are of significant agronomic value worldwide due to their potent and highly specific activity against various insect orders. However, some of these pore-forming toxins display specific activity against a range of human cancer cells whilst possessing no known insecticidal activity; Cry41Aa is one such toxin. Cry41Aa has similarities to its insecticidal counterparts in both its 3-domain toxic core structure and pore-forming abilities, but how it has evolved to target human cells is a mystery.
View Article and Find Full Text PDFThe development of a safe and effective vaccine is essential to protect populations against coronavirus disease 2019 (COVID-19). There are several vaccine candidates under investigation with different mechanisms of action. In the present study, we have evaluated the safety and immunogenicity of a recombinant receptor-binding domain (RBD)-based protein subunit vaccine (Noora vaccine) against COVID-19 in adults.
View Article and Find Full Text PDFBMJ Open
April 2022
Background: Cleaning is a major control component for outbreaks of infection. However, for the SARS-CoV-2 pandemic, there is limited specific guidance regarding the proper disinfection methods that should be used.
Methods: We conducted a systematic review of the literature on cleaning, disinfection or decontamination methods in the prevention of SARS-CoV-2.
In this paper, an incorporated bridge-type superconducting fault current limiter (BSFCL) and Dynamic Voltage Restorer (DVR) is presented to improve the voltage quality and limiting fault current problems in distribution systems. In order to achieve these capabilities, the BSFCL and DVR are integrated through a common DC link as a BSFCL-DVR system. The FCL and DVR ports of the BSFCL-DVR system are located in the beginning and end of the sensitive loads' feeder integrated to the point of common coupling (PCC) in the distribution system.
View Article and Find Full Text PDFWorld J Plast Surg
May 2019
Background: Microvascular surgery is one of the most important parts of reconstructive surgery. In the present study, the effect of ethanol on microvascular diameter and prevention of thrombosis was evaluated.
Methods: Totally, 80 vessels including 40 arteries and 40 veins in right and left ears of 20 adult rabbits were enrolled.
World J Plast Surg
May 2019
Background: Basal cell carcinomas (BCCs) are locally invasive periocular skin cancers affecting lower eyelids more than upper eyelids. The purpose of this study was to describe techniques used for lower eyelid reconstruction after extended excision of BCC.
Methods: Eight referred patients with BCC who underwent lower eyelid reconstruction were enrolled.
Cystic echinococcosis is of great public health importance. Surgery is the efficient treatment for this infection. To minimize the risk of cyst intraoperative leakage, using scolicidals is crucial.
View Article and Find Full Text PDFFor the first time, prediction accuracies of some supervised and unsupervised algorithms were evaluated in an SSR-based DNA fingerprinting study of a pea collection containing 20 cultivars and 57 wild samples. In general, according to the 10 attribute weighting models, the SSR alleles of PEAPHTAP-2 and PSBLOX13.2-1 were the two most important attributes to generate discrimination among eight different species and subspecies of genus Pisum.
View Article and Find Full Text PDFNucleosides Nucleotides Nucleic Acids
April 2014
Seven ab initio web-based gene prediction programs (i.e., AUGUSTUS, BGF, Fgenesh, Fgenesh+, GeneID, Genemark.
View Article and Find Full Text PDFTo diminish the time required for some diagnostic assays including reverse transcription PCR (RT-PCR), reverse transcription loop-mediated isothermal amplification (RT-LAMP; due to mainly RNA extraction step) and also DAS-ELISA into a minimum level, an innovative immunocapture RT-LAMP (IC-RT-LAMP) and immunocapture reverse transcription (IC/RT-PCR) protocol on the basis of Potato Leafroll virus (PLRV) genome were used and optimized. In this regard, all six IC-RT-LAMP primers (i.e.
View Article and Find Full Text PDFPhys Rev E Stat Nonlin Soft Matter Phys
April 2012
We study a nanoscale system composed of one corrugated plate (rack) and one corrugated cylinder (pinion) coupled via the lateral Casimir force. We assume that the rack moves uniformly. The axle of the pinion experiences frictional torque and random torque due to a surrounding fluid.
View Article and Find Full Text PDFPhys Rev E Stat Nonlin Soft Matter Phys
September 2010
We study a nanoscale system composed of one corrugated cylinder (pinion) and one corrugated plate (rack). The pinion and rack have no mechanical contact, but are coupled via the lateral Casimir force. We consider the case where the rack position versus time is a periodic triangular signal.
View Article and Find Full Text PDFPhys Rev E Stat Nonlin Soft Matter Phys
July 2010
We study a nanoscale system composed of one corrugated cylinder (pinion) placed between two corrugated plates (racks). The pinion and racks have no mechanical contact, but are coupled via the lateral Casimir force-one of the most spectacular consequences of quantum fluctuations of the electromagnetic field. The noncontact design of the device could help with the noteworthy wear problem in nanoscale mechanical systems.
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