Aflatoxin is a toxic metabolite produced mainly by spp. which may occur in dairy products because of biotransformation. In this work, a systematic and meta-analysis approach has been considered on the topic of aflatoxin M1 (AFM1) content in dairy Iranian products.
View Article and Find Full Text PDFAniline exposure leads to neuron and spleen toxicity specifically and makes diverse neurological effects and sarcoma that is defined by splenomegaly, hyperplasia, and fibrosis and tumors formation at the end. However, the molecular mechanism(s) of aniline-induced spleen toxicity is not understood well, previous studies have represented that aniline exposure results in iron overload and initiation of oxidative/nitrosative disorder stress and oxidative damage to proteins, lipids and DNA subsequently, in the spleen. Elevated expression of cyclins, cyclin-dependent kinases (CDKs) and phosphorylation of pRB protein along with increases in A, B and CDK1 as a cell cycle regulatory proteins cyclins, and reduce in CDK inhibitors (p21 and p27) could be critical in cell cycle regulation, which contributes to tumorigenic response after aniline exposure.
View Article and Find Full Text PDFMed J Islam Repub Iran
October 2015
Background: Chlorinated pesticides have been used in pest control for several decades in the world. These compounds are still applied in many regions, and their continuous usage has resulted in their bioaccumulation and residue in the food chain. These residues could transfer to food products and accumulate in fat tissues.
View Article and Find Full Text PDFBackground: The German cockroach, Blattella germanica is a major hygienic pest and mechanical vector for pathogenic agents in hospitals and residential areas. The development of insecticide resistance is a serious problem in controlling of this pest. Toxicity of four commonly used insecticides (permethrin, cypermethrin, malathion and chlorpyrifos) against two hospital- collected strains of the German cockroach was investigated.
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