The impact of exosomes on bone health: A focus on osteoporosis.

Osteoporosis is a widespread chronic condition. Although standard treatments are generally effective, they are frequently constrained by side effects and the risk of developing drug resistance. A promising area of research is the investigation of extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, which play a crucial role in bone metabolism.

Analytical calculation of beam profile and orbital angular momentum spectrum of Laguerre Gaussian beams reflected from a graphene plasmonic structure.

In this paper, Laguerre Gaussian (LG) beams with different topological charges are used for excitation of surface plasmon polaritons (SPPs) through a graphene layer inserted in the Otto-configuration. By utilizing the angular spectrum representation (ASR) and Lorenz-gauge vector potential, an explicit analytical expression is derived for the electromagnetic fields of the reflected beam. At the optimal excitation state of graphene SPPs, the reflected beam exhibits a distinctive field profile characterized by two identical crescent-shaped lobes separated by a vertical strip with null intensity.

Role of non-coding RNAs in osteoporosis.

Osteoporosis, a prevalent bone disorder influenced by genetic and environmental elements, significantly increases the likelihood of fractures and bone weakness, greatly affecting the lives of those afflicted. Yet, the exact epigenetic processes behind the onset of osteoporosis are still unclear. Growing research indicates that epigenetic changes could act as vital mediators that connect genetic tendencies and environmental influences, thereby increasing the risk of osteoporosis and bone fractures.

Assessment of Open-Wedge High Tibial Osteotomy Plus Tibial Tubercle Osteotomy: A Novel Approach for Genu Varum Treatment.

Background: Lower extremity genu varum is a common deformity leading to imbalanced weight distribution on the knee joint and eventually significant disabilities due to medial compartment joint osteoarthritis. This study was aimed to assess the efficacy of a novel technique of high tibial open wedge osteotomy plus tubercle osteotomy in a follow-up study.

Materials And Methods: This is a prospective census cross-sectional study conducted on 146 patients with the history of genu varus undergone high tibial open-wedge osteotomy and tubercle osteotomy since 2011.

Clinical presentation of carpal tunnel syndrome with different severity: a cross sectional study.

Carpal tunnel syndrome is a common neuropathy in the hand which presented with pain and paresthesia in the hands and the wrists. The aim of our study was evaluated clinical symptoms of patients with different severity of CTS. This study is a cross-sectional study was performed on 40 patients referred to Emam khomeyni Hospital in Tehran from 2017 to late 2019 with symptoms of CTS and have been diagnosed with a definite diagnosis.