Spontaneous relapse in patients with inactive chronic hepatitis B virus infection.

Background: Chronic hepatitis B virus infection (HBV) may reactivate during the course of the disease and is called spontaneous relapse. The purpose of this study was to evaluate the incidence of relapse of hepatitis in subjects with inactive HBV carriers.

Methods: This follow-up study was performed on 785 patients with inactive HBV carriers that were followed-up at six month intervals.