Novel 3D printed polysaccharide-based materials with prebiotic activity for potential treatment of diaper rash.

Diaper rash, mainly occurring as erythema and itching in the diaper area, causes considerable distress to infants and toddlers. Increasing evidence suggests that an unequal distribution of microorganisms on the skin contributes to the development of diaper dermatitis. Probiotic bacteria, like Staphylococcus epidermidis, are crucial for maintaining a healthy balance in the skin's microbiome, among others, through their fermentative metabolites, such as short-chain fatty acids.

The overlap of cognitive impairment in depression and schizophrenia: a comparative study.

Background: Schizophrenia (SCH) is primarily a cognitive dysfunction. Its specific cognitive impairment profile was identified and suggestions have been made to include it in present diagnostic instruments as a special differential diagnostic criterion. However, studies indicate a substantial overlap of cognitive deficits between SCH patients and those with depression (DEP).