Publications by authors named "Moises Santana Oliveira"
Evaluation of 2D and 3D Erythroid Differentiation Protocols Using Sickle Cell Disease and Healthy Donor Induced Pluripotent Stem Cells.
Gabriele Louise Soares Martins Carolina Kymie Vasques Nonaka Erik Aranha Rossi Adne Vitória Rocha de Lima Corynne Stephanie Ahouefa Adanho Moisés Santana Oliveira
Cells
April 2023
Background: Sickle cell disease (SCD) is a highly prevalent genetic disease caused by a point mutation in the gene, which can lead to chronic hemolytic anemia and vaso-occlusive events. Patient-derived induced pluripotent stem cells (iPSCs) hold promise for the development of novel predictive methods for screening drugs with anti-sickling activity. In this study, we evaluated and compared the efficiency of 2D and 3D erythroid differentiation protocols using a healthy control and SCD-iPSCs.
View Article and Find Full Text PDFArticle Synopsis
- COVID-19 poses significant risks to patients on renal replacement therapy, as those with kidney disease face severe complications if infected.
- Several medical guidelines have emerged to help manage this vulnerable population, focusing on prevention and safety in dialysis settings.
- The article reviews key strategies for screening and protecting healthcare workers and dialysis patients, along with emergency responses to outbreaks and management of complications, including special considerations for children with kidney disease.