Publications by authors named "Moises Apolaya-Segura"
Aim: To evaluate the biochemical and hematological markers associated with the risk of death due to COVID-19 in a clinical cohort with a severe clinical profile.
Methods: A retrospective study was conducted among 215 anonymized inpatient records from the Hospital Nacional Almanzor Aguinaga Asenjo, Peru, between April and June 2020. The association between biomarkers and death due to COVID-19 was assessed using Cox regression, with a multivariable modeling of 1) biochemical and 2) hematological markers.
Article Synopsis
- Ivermectin is reviewed as a treatment for various parasitic diseases in Peru, emphasizing its effectiveness against strongyloidiasis, scabies, lice, and more.
- The optimal dosages for effective treatment range between 150 to 400 μg/kg, depending on the specific disease, with caution advised due to potential ocular side effects at higher doses.
- The study supports ivermectin's safety for children under 15 kg and highlights the urgent need for its use in Peru due to a high prevalence of intestinal and ectoparasites in the population.
Background: The inactivated virus vaccine, BBIBP-CorV, was principally distributed across low- and middle-income countries as primary vaccination strategy to prevent poor COVID-19 outcomes. Limited information is available regarding its effect on heterologous boosting. We aim to evaluate the immunogenicity and reactogenicity of a third booster dose of BNT162b2 following a double BBIBP-CorV regime.
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- * A study in Peru assessed the impact of COVID-19 vaccination on the emotional health of adults aged 60-79, comparing outcomes before and after vaccination.
- * Results showed that older adults who received two doses of the vaccine experienced significantly less fear and anxiety regarding COVID-19, suggesting that the benefits of vaccination extend beyond physical health.
Background: Patients with chronic kidney disease have a higher risk of severe disease and mortality from COVID-19 than the general population.
Objective: To compare hospitalization and mortality rates during the pandemic among chronic hemodialysis (HD) patients and the general population in Lima (Peru).
Methods: This retrospective cohort included an assessment of the database of chronic HD patients of the health service providers of the social health insurance benefit networks of Lima and Callao between 2019 and 2021.
Objective: To estimate the prevalence of post-vaccination seropositivity against SARS-CoV-2 and identify its predictors in Peruvian Social Health Insurance (EsSalud) personnel in 2021.
Methods: We conducted a cross-sectional study in a representative simple stratified sample of EsSalud workers. We evaluated IgG anti-SARS-CoV-2 antibodies response (seropositivity) by passive (previous infection) and active immunization (vaccination), and epidemiological and occupational variables obtained by direct interview and a data collection form.
Clinical-epidemiologic variation in patients treated in the first and second wave of COVID-19 in Lambayeque, Peru: A cluster analysis.
Int J Infect Dis
October 2022
Objectives: To identify differences in the clinical and epidemiologic characteristics of patients during the first and second waves of the COVID-19 pandemic at the EsSalud Lambayeque health care network, Peru.
Methods: An analytical cross-sectional study of 53,912 patients enrolled during the first and second waves of COVID-19 was conducted. Cluster analysis based on clustering large applications (CLARA) was applied to clinical-epidemiologic data presented at the time of care.
Background: dropout is considered a problem because attention is interrupted, causing in many cases, complications and important sequelae. The prevalence and factors associated with outpatient referral (DECE) in a national hospital in Peru, 2014-2015, were evaluated.
Methods: analytical cross-sectional design.
[Influence of voluntary military service on the sexual behavior of a population of young adults].
Rev Peru Med Exp Salud Publica
July 2013
Objectives: To determine if having done the voluntary military service is related to the sexual behavior of a population of young adults.
Materials And Methods: A cross-sectional study was carried out, which involved cadets enrolled in the Peruvian Air Force Sub Officer Academy of Peru, in 2010. For this study, civilians, as well as personnel who had performed voluntary military service, anonymously answered a self-administered questionnaire about their knowledge regarding HIV transmission and sexual risk behaviors.
Objective: To identify the factors associated with level of knowledge and attitudes toward research among undergraduate medical students in Peru.
Methods: In this analytical cross-sectional study, a validated questionnaire on knowledge, attitudes, and practices related to research was applied to a representative sample of students at 17 Peruvian medical schools. The categorical and quantitative variables were subjected to simple two-factor analysis with adjustment for intraclass correlation.