Publications by authors named "Mohsen Sheikhi"
Objectives: Human T cell leukemia virus-1 (HTLV-1) infection may lead to one or both diseases including HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) or adult T cell leukemia lymphoma (ATLL). The complete interactions of the virus with host cells in both diseases is yet to be determined. This study aims to construct an interaction network for distinct signaling pathways in these diseases based on finding differentially expressed genes (DEGs) between HAM/TSP and ATLL.
View Article and Find Full Text PDFArticle Synopsis
- * Researchers analyzed gene expression differences between normal individuals, asymptomatic carriers, and patients with ATLL and HAM/TSP to identify key genes involved in these conditions.
- * Findings revealed important biological pathways linked to cell growth, immune response, inflammation, and cancer that could guide future drug development targeting HTLV-1 related diseases.