Dialysis rolled scaffold bioreactor allows extended production of monoclonal antibody with reduced media use.

Rapidly expanding biopharmaceutical market demands more cost-effective platforms to produce protein therapeutics. To this end, novel approaches, such as perfusion culture or concentrated fed-batch, have been explored for higher yields and lower manufacturing costs. Although these new approaches produced promising results, but their wide-spread use in the industry is still limited.

Magnesium supplementation and insulin resistance in patients with rheumatoid arthritis.

Rheumatoid arthritis (RA) is a multifactorial disease affecting the immune system and many tissues in the body. This study aimed to evaluate the effect of magnesium supplementation on insulin resistance and fasting blood sugar (FBS) of patients with RA. In this prospective uncontrolled before-after study, RA patients referring to Rheumatology clinics of Qom City from January 2020 to January 2021 were evaluated.

Haemostasis. Part 2: Medications that affect haemostasis.

Post-operative haemorrhage is a recognized complication in dental practice. This may be more prevalent in patients taking antithrombotic medications. It is important that the dentist understands the mechanism of action of these drugs and how they may affect management of dental patients.

Metal concentrations in tissues of two fish species from Qeshm Island, Iran.

The purpose of this study was to determine the concentrations of metals, cadmium, chromium, lead and nickel in Liza vaigiensis and Johnius carutta, in order to: compare metal concentrations between two species with different gender, and to determine the significance between metal concentrations in the gill, liver and muscle. The highest mean concentrations of cadmium, chromium, lead and nickel in different tissues of these two fish species were found in the liver of L. vaigiensis at 0.

Comparison of the metal concentrations in the feathers of three bird species from southern Iran.

This study was conducted to determine the concentration of metals, namely cadmium, lead, cobalt and copper, in the feathers of chukar (Alectoris chukar), see-see partridge (Ammoperdix griseogularis) and rock dove (Columba livia) in order to: examine the species, gender and age related variations in trace metal accumulation, and identify any relationships between species. Bird samples were collected in February 2012 from the Hormod protected area, southern Iran and the concentration of metals were measured using a Shimadzu AA 660 flame atomic absorption spectrophotometer. The concentrations in all three species were copper > lead > cadmium > cobalt.