Anti Leishmanial Effect of (Ovate) and White Vinegar on Lesion in BALB/c Mice.

Background: is the etiologic agent of zoonotic cutaneous leishmaniasis in Iran, and glucantime injection is currently used for its treatment. This study aimed to evaluate the anti-leishmanial effect of topical and white vinegar in infected BALB/c mice.

Methods: Thirty infected mice were divided into five groups as follows: Group 1: treated with the combination of ovata powder and white vinegar, Group 2: treated with glucantime, Group 3: treated with white vinegar, Group 4: treated with the combination of ovata powder and water, and Group 5: without any treatment.

Green synthesis of silver nanoparticles (AgNPs) by Pistacia terebinthus extract: Comprehensive evaluation of antimicrobial, antioxidant and anticancer effects.

In recent years, because of the various functions associated with silver nanoparticles (AgNPs) in manufacturing, different ways for their synthesis have been established. The antioxidant and antibacterial effects of terebinth (Pistacia terebinthus) have been proven. In this study, for the first time, using the extract of terebinth, we have synthesized AgNPs using a green method.

Green tea intake and its effect on laboratory parameters and disease symptoms in hospitalised patients with Covid 19: a structured protocol for a randomized controlled trial.

Objectives: The current randomized controlled trial (RCT) will be conducted to assess the effect of green tea intake on disease symptoms and laboratory parameters including C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and complete blood count (CBC) in patients with mild-to-moderate Covid-19 infection.

Trial Design: Randomized, double-blinded, parallel (1:1 ratio) clinical trial exploratory study PARTICIPANTS: We will recruit patients with COVID-19 infection admitted to Yasuj Shahid Jalil Hospital in Yasuj City, Kohgiluyeh and Boyer-Ahmad Province, Iran. Participants' inclusion criteria are as follows: Inclusion Criteria Patients aged ≥18 years COVID-19 diagnosis according to real-time polymerase chain reaction (RT-PCR) Exclusion Criteria Pregnancy or lactation Disseminated intravascular coagulation or any other types of coagulopathy Severe congestive kidney failure Having a history of participating in a clinical trial during the last 30 days INTERVENTION AND COMPARATOR: Intervention: Two capsules containing 450 mg green tea extract along with routine treatment for COVID-19 patients in the intervention group.

Active immunization using exotoxin A confers protection against Pseudomonas aeruginosa infection in a mouse burn model.

Background: Pseudomonas aeruginosa is an important cause of nosocomial infection and may lead to septicemia and death. We evaluated the immunogenicity of semi-purified exotoxin A from the bacterium in a mouse burn model.

Methods: The toxoid was prepared from exotoxin A taken from toxigenic strains of P.