Tibial Nerve Repair in a Dog Model: Effect of Local and Systemic Administration of Erythropoietin.

Purpose: This study aimed to assess the effectiveness of erythropoietin (EPO) as a novel treatment for peripheral nerve injury after surgical repair of an induced tibial nerve injury in dogs.

Methods: Mongrel dogs (n = 27) were randomly divided into three equal groups. A complete tibial nerve injury was induced and repaired directly by stay sutures and the local application of 1 mL fibrin glue (control group).

Mitigation of -induced ileitis by infection pinpointing immunomodulation.

The current study sought to investigate the potential role of infection in the treatment of -induced ileitis. Forty male Swiss albino mice were divided into four groups:a normal control group Igiven only phosphate-buffered saline (PBS), Group II givenPBS for 28 days then infected with cysts for the induction of gastroenteritis, Group III infected only with larvae, and Group IV concurrently infected with larvae, then 28 days post infection, enteritis was induced by oral inoculation with cysts. Histopathologicaland immunohistochemicalassessmentswere performed to determine the levels of inflammatory markers nuclear factor- κB (NF-κB) and myeloperoxidase in the ileum samples.

Intercostal, ilioinguinal, and iliohypogastric nerve transfers for lower limb reinnervation after spinal cord injury: an anatomical feasibility and experimental study.

OBJECTIVESpinal cord injury (SCI) has been investigated in various animal studies. One promising therapeutic approach involves the transfer of peripheral nerves originating above the level of injury into those originating below the level of injury. The purpose of the present study was to evaluate the feasibility of nerve transfers for reinnervation of lower limbs in patients suffering SCI to restore some hip and knee functions, enabling them to independently stand or even step forward with assistive devices and thus improve their quality of life.

Incidence of Toxoplasmosis gondii in Najran region, KSA.

Toxoplasmosis is an endemic disease all over the world. In surveying 210 individuals randomly selected from Najran area for anti-Toxoplasma IgG and IgM using ELISA, IgG was detected in 67 cases (31.9%) of the examined sera.

Evaluation of protective immunity of 28KD-GST as a vaccine against experimental Schistosoma mansoni.

Schistosoma mansoni GST was purified from adult worm homogenates by affinity chromatography. SDS-PAGE analysis of the purified antigen revealed that SmGST has molecular weight around 28 KD was used as a vaccine in a dose of 25 and 35 microg. Eleven groups of BALB/c mice of 10 mice each were vaccinated by GST.

Detection of altered secondary lymphoid-tissue chemkine responsiveness in Balb/c mice infected with Schistosoma mansoni.

To determine the extent to which Balb/c mice splenic T cells were affected by S. mansoni infection, this study aims to investigate the ability of the T cells to produce interferon (IFN)-&, and their chemotactic ability at 7 weeks post-infection. The splenic T cells were capable of producing levels of IFN-& comparable with splenic T cells from naive mice.

Detection of anti-Fasciola isotypes among patients with fascioliasis before and after treatment with Mirazid.

Stool examination using modified Kato thick smear method was performed to detect Fasciola eggs and other parasites. Abdominal pain was the major presenting symptom (87.7%) followed by pallor (83.

Dot ELISA for measuring anti-Fasciola IgG isotypes among patients with fascioliasis.

Stool examination using modified Kato thick smear method was performed to detect Fasciola eggs and other parasites. Forty-five patients were proved to have Fasciola infection by passing eggs in their stool samples. Pallor was the major presenting symptom (95.

Assessing the morbidity of schistosomiasis by measuring eosinophil cationic protein in serum.

Eosinophil cationic protein (ECP) was recently used for assessment of Schistosoma haematobium morbidity. In this study, the level of (ECP) in sera of schistosomiasis patients was significantly higher than control group, and this significance was higher in S. haematobium than S.

Detection of E. histolytica, G. lamblia and Cryptosporidium copro-antigens in stool samples.

A double antibody sandwich ELISA technique, using a chromatography purified antisera against E. histolytica, G. lamblia and Cryptosporidium antigens, was applied to detect copro-antigens of the corrosponding parasites in 90 patients.