Increasing the anticancer activity of azidothymidine toward the breast cancer via rational design of magnetic drug carrier based on molecular imprinting technology.

Cancer treatment based anticancer drugs face serious obstacles. To prevail these obstacles, an effective targeted drug carrier can be imperative. This study aimed to design rationally an imprinting strategy for the carrying of a model anticancer drug, Azidothymidine via molecular imprinting technology.

Electrochemical sensing of 2-methyl-4, 6-dinitrophenol by nanomagnetic core shell linked to carbon nanotube modified glassy carbon electrode.

Electrochemical behavior and sensing of 2-methyl-4, 6-dinitrophenol as an herbicide has been investigated by cyclic voltammetry (CV) and square wave voltammetry (SWV). We have synthesized a cefazolin (CEF) immobilized nanomagnetic core-shell (FeO@SiO-(CH)-CEF) and attached it on the modified glassy carbon electrode (GCE/MWCNT) through electrostatic adsorption (GCE/MWCNT/CEF-SiO@FeO). 2-Methyl-4, 6-dinitrophenol has an oxidation peak that is related to the formation of nitrosamine from hydroxylamine species.

Spectrophotometric determination of nitrite in soil and water using cefixime and central composite design.

The present paper seeks to develop a simple method for the spectrophotometric determination of nitrite in soil and water samples and also measure optimum reaction conditions along with other analytical parameters. The method is based on the diazotization-coupling reaction of nitrite with cefixime and 1-naphthylamine in an acidic solution (Griess reaction). The final product that is an azo dye has an orange color with maximum absorption at 360 nm which Beer's Law is obeyed over the concentration range 0.

Room-temperature ionic liquids as electrolytes in electroanalytical determination of traces of 2-furaldehyde from oil and related wastewaters from refining processes.

Three different ionic liquids, 1-ethyl-3-methylimidazolium tetrafluoroborate, [EMIM][BF(4)]; 1-butyl-3-methylimidazolium trifluoromethanesulfonate, [BMIM][OTf]; and 1-butyl-1-methylpyrrolidinium bis(trifluoromethanesulfonyl)imide [bmpyrr][NTf(2)] were studied as electrolytes in the electroanalytical quantification of 2-furaldehyde using square wave and differential pulse voltammetries. On applying a cathodic scan, a well-defined 2-electron wave was observed corresponding to the reduction of 2-furaldehyde to furfuryl alcohol. The electrochemical stability of the ionic liquids as electrolytes for analytical aspects and electrokinetic studies was investigated using a glassy carbon electrode (GCE).

31P NMR study of the stoichiometry, stability and thermodynamics of complex formation between palladium(II) acetate and bis(diphenylphosphino)ferrocene.

The complexation reaction between palladium (II) acetate, and 1,1'-bis(diphenylphosphino)ferrocene, DPPF, was investigated in two different deuterated solvents CDCl(3) and DMSO at various temperatures using (31)P NMR spectroscopy. The exchange between free and complexed DPPF is slow on the NMR time scale and consequently, two (31)P NMR signals were observed. At metal ion-to-ligand mole ratio larger than 1, only one (31)P NMR signal was observed, indicating the formation of a 1:1 Pd(2+)-DPPF complex in solution.

Spectroscopic and conductometric studies of molecular complex formation between 2,4,6-trinitrophenol and diaza-18-crown-6, tetraaza-14-crown-4 and cryptand C222 in 1,2-dichloroethane solution.

The formation of molecular complexes between 2,4,6-trinitrophenol (TNP) and aza-substituted macrocycles diaza-18-crown-6 (DA18C6), tetraaza-14-crown-4 (TA14C4) and cryptand C222 in 1,2-dichloroethane solution was investigated spectrophotometrically and conductometrically. The mole ratio and continuous variations studies based on both physicochemical techniques employed clearly revealed the formation of both 1:1 and 2:1 (TNP:macrocycle) adducts in solution. Formation of the resulting complexes was also confirmed by 1H NMR and IR spectroscopic studies.