Effect of chrysin on nociception in formalin test and serum levels of noradrenalin and corticosterone in rats.

Objective: The levels of corticosterone and noradrenalin as the two nociception modulators modify after stress condition. The propose of current study was to investigate the effect of chrysin on formalin-induced nociceptive behaviors and serum levels of corticosterone and noradrenalin in rats.

Materials And Methods: Pain was induced by applying 20 μL of 5% formalin in distilled water in the subplantar of the right hind paw.