Molecular Background of RhD-positive and RhD-negative Phenotypes in a Saudi Population.

Background: The gene is one of the most complex blood group genes. The molecular background of the gene in RhD-negative and RhD-positive individuals varies within and among different populations. Knowing the molecular basis of the gene in a specific population is required to establish effective genotyping methods.

Frequency of Rh and K antigens in blood donors in Riyadh.

Objectives: Investigate the prevalence of Rh and the K antigens and their phenotypes in the red blood cells of blood donors in Riyadh, Saudi Arabia.

Methods: This is a retrospective study. The five principal Rh antigens (D, C, c, E, e) and the Kell antigen from the Kell blood group were tested in 4,675 random samples collected from four blood bank centers in Riyadh.