Publications by authors named "Mohit A Upadhye"
Article Synopsis
- B cells play a crucial role in multiple sclerosis, highlighted by the effectiveness of therapies that deplete B cells, but their exact contribution to the disease is still not fully understood.
- This study used a specific mouse model of autoimmune encephalomyelitis to show that depleting B cells reduces disease progression and T cell activation related to a myelin protein.
- The researchers found that B cells are essential for presenting antigens to CD4 T cells, which is key in causing the disease, suggesting that understanding these interactions can help develop new treatments for autoimmune diseases.
