Publications by authors named "Mohindra S"

Portal cavernoma cholangiopathy refers to changes in the intrahepatic and extrahepatic biliary ducts in patients with extrahepatic portal venous obstruction. Spontaneous hemobilia in the setting of portal cavernoma cholangiopathy is extremely rare, and it poses diagnostic as well as therapeutic challenge. Here, we report the case of a 10-year-old girl with extrahepatic portal venous obstruction, who presented with hemobilia.

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Background And Aims: Postoperative pain can impede functional recovery and delay hospital discharge after functional endoscopic sinus surgery (FESS). The study aimed to assess the efficacy of ultrasound (USG)-guided suprazygomatic maxillary nerve block (SZMNB) for postoperative pain in FESS.

Methods: Forty-eight adult patients between 18 and 65 years of age with American Society of Anesthesiologists physical status I and II and scheduled to undergo FESS were enroled in this randomised controlled study.

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Hemophagocytic lymphohistiocytosis syndrome (HLH) is a rare hyperinflammatory disorder linked to acute pancreatitis. While there are only a few case reports available on this particular association, we would like to share the case of a 60-year-old man who experienced acute-onset abdominal pain typical of pancreatitis. Three days after admission, he developed fever, pancytopenia, hypertriglyceridemia, and hyperferritinemia.

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Neurosurgical residency is tough. Grueling hours and tough decisions require a mental makeup unlike many other specialties. But the real examination begins after the residency is over.

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Cardiac lipomatous hypertrophy is a rare benign condition almost exclusively involving the interatrial septum. Interventricular septum involvement is seldom noted, with only a few documented case reports demonstrating the finding on various modalities such as ECHO, CT, and MRI. FDG PET can be a surrogate marker for lipomatous hypertrophy of the interventricular septum.

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Extrahepatic portal vein thrombosis (EHPVO) is an uncommon cause of portal hypertension. In the long term, patients may develop portal cavernoma cholangiopathy (PCC). Up to 30%-40% of patients with EHPVO may not have shuntable veins and are often difficult to manage surgically.

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Article Synopsis
  • The study investigates how osmotherapeutic agents, specifically mannitol and hypertonic saline (HTS), affect cardiac output and blood flow in elderly patients undergoing brain surgery.
  • Researchers analyzed 28 patients over 65 years, comparing the impacts of 20% mannitol and 3% HTS through transesophageal echocardiography at various time points after infusion.
  • Results showed significant improvements in left ventricular outflow tract velocity time integral and cardiac output in the HTS group compared to the mannitol group, indicating HTS may better support heart function while providing similar brain relaxation benefits in this population.
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Aim: To analyze clinical and imaging characteristics of post-traumatic posterior fossa extradural hematoma (PFEDH).

Material And Methods: Between 2018 and 2022, 51 patients were admitted to our tertiary care trauma center with a diagnosis of PFEDH. The management decision was tailored by an individual consultant based on clinicoradiological findings.

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  • The study investigates the effectiveness of transgastric percutaneous drainage (PCD) for treating retrogastric walled-off pancreatic necrosis (WOPN) in patients with acute pancreatitis.
  • A total of 44 patients were analyzed, revealing a high technical success rate of 93% for drain placement and 91% success in drain internalization among those who underwent it.
  • Results indicate that successful internalization of the drain leads to shorter hospital stays and reduced complications, promoting quicker recovery and less need for further procedures.
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Background: Decompressive neurosurgery is recommended for patients with cerebral venous thrombosis (CVT) who have large parenchymal lesions and impending brain herniation. This recommendation is based on limited evidence. We report long-term outcomes of patients with CVT treated by decompressive neurosurgery in an international cohort.

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Background: Autoimmune hepatitis (AIH) is uncommon and predominantly affects females. Data on AIH from India are scanty. We retrospectively analyzed the spectrum and outcome of adults with AIH and compared it between male and female patients.

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Article Synopsis
  • - Meniere's Disease, a rare ear disorder causing significant patient distress, has no definitive treatment, with Endolymphatic hydrops being a key complication, although its exact cause remains unknown.
  • - A study involving 25 patients with Meniere's Disease found that 56% had allergies, with airborne allergens being more prevalent than food allergens, and tyrophagus being the most common allergen identified.
  • - Despite high allergy prevalence, no significant correlation was found between allergy status and the severity of symptoms, but managing specific allergens may help reduce symptoms for patients with associated allergies.
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Background: Sexual dysfunction significantly affects interpersonal relationships and overall quality of life. It remains a matter of concern for risk assessment and counseling in patients with ruptured intracranial aneurysms.

Objective: To assess the sexual dysfunctions in patients undergoing clipping for ruptured intracranial aneurysms and comparative evaluation among different anterior circulation aneurysms.

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Background: Primary hyperparathyroidism (PHPT) is rarely associated with the occurrence of acute or chronic pancreatitis, requiring complex perioperative management. This study aimed to assess the prevalence and disease characteristics of pancreatitis in PHPT.

Materials And Methods: This study is a clinicopathological analysis of the medical records of patients who were diagnosed with PHPT with pancreatitis between 1989 and 2021 in the Endocrine Surgery department, SGPGI, Lucknow.

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Background: Post-endoscopic retrograde cholangio-pancreatography pancreatitis (PEP) is seen in 3% to 16% of children undergoing therapeutic endoscopic retrograde cholangio-pancreatography (ERCP). We evaluated the risk factors of PEP and utility of 4-hour post-ERCP amylase and lipase for early prediction of PEP in children with chronic pancreatitis (CP).

Materials And Methods: Thirty children with CP (boys 20, 14.

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Background: Traumatic brain injury, being a notorious cause of mortality and morbidity across the globe, presents with a variety of lesions. One of the distinct patterns of injury is characterized by contusions of both frontal lobes, labeled "traumatic bifrontal contusions" (TBCs). TBC is often associated with the presence of significant edema and mass effect leading to rapid clinical deterioration after a usually benign presentation at the time of first evaluation.

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Article Synopsis
  • * The study reports on two children diagnosed with BRBNS, one experiencing obscure bleeding and the other with overt bleeding, both exhibiting cutaneous lesions that aided in diagnosis.
  • * Successful treatments included endoscopic band ligation and nonselective beta-blockers, improving hemoglobin levels, emphasizing the need for gastroenterologists to recognize this uncommon disorder for effective diagnosis and management.
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Lymphoplasmacyte-rich meningioma (LP meningioma) is a rare form of grade 1 meningioma. It shows dense lymphoplasmacytic infiltrate, mimicking an inflammatory lesion. We present a case of Lymphoplasmacyte-rich (LP) meningioma in the left parasagittal region in a 47-year-old female.

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Allergic rhinitis affects 30% of the Indian population (Dey et al. in Int Arch Allergy Immunol 178:60-65, 2019). Patients can be sensitive to single or multiple allergens.

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Objectives: In conventional endoscopic retrograde cholangiopancreatography (ERCP), the patient lies prone or in a semi-prone position under deep sedation and maintains spontaneous ventilation. Sedative-induced respiratory depression and unprotected airway compromise patients' safety. The gastro-laryngeal tube (G-LT) is a novel reusable supraglottic airway device with two separate ports for endoscopy and ventilation.

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Objective: Application of surgical skull pins causes hemodynamic fluctuations in neurosurgical procedures. To reduce this response, we describe the use of a novel nonpharmacologic method in the form of medical-grade sterile silicone studs to cushion the pressure of the skull pin in the adult population. This study aimed to evaluate the use of conventionally used fentanyl and medical-grade sterile silicone studs for the prevention of hemodynamic response to skull pin insertion.

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Introduction: Ampullary adenocarcinoma is a rare neoplasm often treated by the complex Whipple's procedure. Several histological factors predict poor prognosis including pancreatobiliary morphology, presence of lymphovascular, perineural invasion and local or distant metastasis. Systemic therapy with gemcitabine, 5-fluorouracil regimens are given with variable benefits.

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Article Synopsis
  • The study aimed to create phonemically balanced passages in Punjabi, designed to reflect the sound distribution in the spoken language using familiar words.
  • Five speech-language pathologists validated the passages, after which 100 participants with normal hearing were tested for nasalence while reading them.
  • The results showed varying nasalence scores for the different types of passages, indicating good reliability for assessing resonance disorders in Punjabi speakers.
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