Publications by authors named "Mohd Zubair Baba"
Int J Biol Macromol
November 2024
Article Synopsis
- The study focuses on developing solid lipid nanoparticles (SLNs) loaded with the chemotherapy drug irinotecan and the isoflavonoid daidzein, coated with materials like hyaluronic acid for targeted delivery to colon cancer cells.
- These nanoparticles were characterized for size, charge, and compatibility, revealing spherical shapes, high entrapment efficiency, and effective drug release patterns.
- In vitro and in vivo tests showed that these SLNs reduced cancer cell viability, promoted cell cycle arrest, and improved colon tissue structure, suggesting great potential for treating colon cancer.
