Publications by authors named "Mohd Ahmed Khan"
Article Synopsis
- - We used parallel-tempering molecular dynamics simulations to explore how temperature and size affect the shapes of copper (Cu) nanocrystals with 100 to 200 atoms, finding that shape transitions happen often at different temperatures.
- - Our calculations also revealed that the vibrational entropy encourages shapes that are between a decahedron and an icosahedron, suggesting that using minimum-energy calculations may not accurately reflect shapes at real-world temperatures.
- - We noticed that even small size changes in nanocrystals, sometimes by just one atom, can lead to significant alterations in their shapes, which may help in developing methods for creating specific nanocrystal shapes.
This research aims to coat Teriflunomide (TEF) loaded conventional nanoliposomes (CON-TEF-LIPO) with Chondroitin sulphate (CS) to produce CS-TEF-LIPO for the effective treatment of Rheumatoid arthritis (RA). Both CON-TEF-LIPO and CS-TEF-LIPO were produced, characterized and evaluated for their active targeting potential towards CD44 receptors. Cell cytotoxicity, cell viability and intracellular uptake study on differentiated U937 and MG-63 cells demonstrated the active targeting of CS-TEF-LIPO towards CD44 receptors.
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