Assessment of Toxicity of Green Synthesized Silver Nanoparticle-coated Titanium Mini-implants with Uncoated Mini-implants: Comparison in an Animal Model Study.

Aim: To assess the potential for systemic toxicity when silver nanoparticle-coated mini-implants were implanted in Wistar albino rats conducted as a comparative study in the animal model by assessing the blood biochemistry, liver and kidney function, and histology of the implanted site.

Materials And Methods: The surface of the mini-implant was coated with a green-mediated silver nanoparticle. Uncoated mini-implants were placed in two groups of eight Wistar albino rats, and silver nanoparticle-coated mini-implants were placed in another eight rats.

Nano-fibre matrix loaded with multi-nutrients to achieve balanced crop nutrition in greengram (Vigna radiata L.).

This research paper focuses on exploring the possibility of delivering macro, micro and trace elements using seed encapsulation through nano-fibres that are known to improve the nutrient use efficiencies while reducing the loss of nutrients. The nano-fibres were developed using an electrospinning machine by subjecting the polymer solution (10% polyvinyl alcohol PVA) loaded with recommended quantities of nutrients under optimal solution (pH, concentration, viscosity) and process (voltage, flow rate, tip-to-collector distance) parameters. The nano-fibres were characterized using SEM, TEM, FT-IR, XRD, TGA and Impedance spectra besides nutrient release pattern by ICP-MS.

A study on structural characterization of potential impurities of Sugammadex sodium using LC/ESI/QTOF/MS/MS and NMR.

The first selective relaxant binding agent (SRBA), Sugammadex sodium (SGS) is used to reverse anesthesia. A study of the process related and degradation products will help to optimize process parameters and also to develop the analytical methods and set the quality standard for a quality control strategy in pharmaceutical industry. During the manufacture of SGS, all the process related impurities are controlled in every stage and process related and degradation products are controlled in the active pharmaceutical ingredient (API) as per ICH guidelines.