Publications by authors named "Mohanad M Odeh"
The scaffolds of two known CDK inhibitors (CAN508 and dinaciclib) were the starting point for synthesizing two series of pyarazolo[1,5-a]pyrimidines to obtain potent inhibitors with proper selectivity. The study presented four promising compounds; 10d, 10e, 16a, and 16c based on cytotoxic studies. Compound 16a revealed superior activity in the preliminary anticancer screening with GI % = 79.
View Article and Find Full Text PDFArticle Synopsis
- Dietary supplements (DSs) are increasingly used by university students in Jordan, with a prevalence rate of over 60%, primarily motivated by health maintenance.
- Despite their widespread use, students demonstrated poor knowledge and a negative attitude towards DSs, alongside risky consumption practices.
- Factors influencing DS use included being of normal weight or overweight, lower family income, and being an undergraduate student, indicating a need for better nutrition education to promote safe DS practices.
Background: The number of COVID-19 infected patients has been soaring in the Middle East countries. The disease poses a significant threat, decisions about prioritizing care should be made in accordance with the proven risk factors for complications.
Objective: The present study provides the first bespoke prediction model in the Middle East to identify COVID-19 patients, who are at higher risk for complications.
Background: A simple and powerful microextraction procedure, the solvent bar microextraction (SBME), was used for the simultaneous determination of two diuretics, furosemide and spironolactone in human urine and plasma samples, using high-performance liquid chromatography coupled with diode array detection (HPLC-DAD).
Methods: The appropriate amount (2 μL) of 1-octanol as an organic solvent confined within 2.5 cm of a porous hollow fiber micro-tube, sealed at both ends was used for this procedure.
Background: Data on COVID-19 in children are limited. This study aimed to identify the clinical characteristics, laboratory results and longitudinal RT-PCR- testing pattern in children infected with theSARS-CoV2 virus and admitted to a hospital in Jordan.
Methods: The study is a retrospective chart review of patients admitted between 16 March and 23 April 2020.