Publications by authors named "Mohanad Abdalrhman"
Article Synopsis
- A recent study examined the use of PASA16 phage therapy in 16 patients with stubborn Pseudomonas aeruginosa infections, highlighting the largest compassionate-use series of its kind.
- The phages were administered either intravenously or topically, showing good results in 13 out of 15 cases, with only minor side effects reported.
- The findings suggest that combining PASA16 with traditional antibiotics is a promising option for patients who haven't responded to standard treatments, paving the way for future clinical trials.
Phage therapy is a promising solution for bacterial infections that are not eradicated by conventional antibiotics. A crucial element of this approach is appropriate matching of bacteriophages and antibiotics to the bacterial target according to the clinical setting. However, there is currently little consistency in the protocols used for the laboratory evaluation of bacteriophages intended for antibacterial treatment.
View Article and Find Full Text PDFspp. are emerging pathogens mainly in nosocomial infections. in particular is involved in urinary tract infections and contributes significantly to the high incidence of biofilm-formation in catheterized patients.
View Article and Find Full Text PDFA key element in phage therapy is the establishment of large phage collections, termed herein "banks", where many well-characterized phages, ready to be used in the clinic, are stored. These phage banks serve for both research and clinical purposes. Phage banks are also a key element in clinical phage microbiology, the prior treatment matching of phages and antibiotics to specific bacterial targets.
View Article and Find Full Text PDF