Introduction: We report three cases of demyelinating disease with tumor-like presentation. This information is particularly important to both neurosurgeons and neurologists who should be aware that inflammatory demyelinating diseases can present as a mass lesion, which is indistinguishable from a tumor, both clinically and radiologically, especially when there is no evidence of temporal dissemination of this disease.
Case Presentation: The first patient was a 42-year-old Malay woman who developed subacute onset of progressive quadriparesis with urinary incontinence.