Investigation of radiation protective features of azadispiro derivatives and their genotoxic potential with Ames/ test system.

Purpose: Five different types of synthesized azadispiro derivatives have been analyzed for radiation absorption capacity and determined their potential to be exploited as substances for a drug to be developed against radiation has been investigated.

Material And Methods: Fast neutron attenuation parameters like the effective mean free path, half-value layer (HVL), removal cross-sections, and neutron transmission number were found with the Monte Carlo simulation Geometry And Tracking (GEANT4) code. Gamma radiation absorption parameters, such as effective atom number (), mean free path (MFP), mass attenuation coefficient (MAC), and half-value layer (HVL) were theoretically determined with WinXCom software.

Investigation of neutron and gamma radiation protective characteristics of synthesized quinoline derivatives.

Purpose: Quinoline is formed by various natural compounds, such as alkaloids from the cinchona plant, which exhibit various biological activities, and is an important building material for the development of new drugs. Quinoline can be used in anti-radiation drug development but radiation interaction properties must be determined.

Material And Methods: In this study, six types of synthesized quinoline derivatives were used.

Components of Metabolic Syndrome at 22 years of Age - Findings From Pune Low Birth Weight Study.

Background: To study the early markers of Metabolic syndrome in a cohort of low birth weight (LBW) children followed up since birth, at the age of 22 years.

Design: Prospective cohort study.

Setting: Tertiary-care hospital.