Association of Forkhead Box O3a (FOXO3a) single - nucleotide polymorphism with bronchial asthma in Egyptian population.

Asthma is a common chronic inflammatory condition with a highly complex genetic predisposition and environmental factors which play an important role in its development. Polymorphism in FOXO3a transcription factor has been linked to a number of inflammatory and respiratory diseases such as bronchiolitis and idiopathic pulmonary fibrosis suggesting that it may be implicated in the pathogenesis of asthma. This study aimed to investigate FOXO3a SNP (rs13217795) association with bronchial asthma and its degree of severity in adult Egyptian population.

Hybrid model for ecological vulnerability assessment in Benin.

Identifying ecologically fragile areas by assessing ecosystem vulnerability is an essential task in environmental conservation and management. Benin is considered a vulnerable area, and its coastal zone, which is subject to erosion and flooding effects, is particularly vulnerable. This study assessed terrestrial ecosystems in Benin by establishing a hybrid ecological vulnerability index (EVI) for 2016 that combined a composite model based on principal component analysis (PCA) with an additive model based on exposure, sensitivity and adaptation.