Publications by authors named "Mohammed S Abohassan"
Res Pract Thromb Haemost
August 2023
Article Synopsis
- Heat shock protein 47 (HSP47) is crucial for collagen production in platelets and plays a significant role in their function when interacting with collagen.
- This study investigates how HSP47 is distributed within platelets and how it affects the signaling of the GPVI collagen receptor, aiming to understand its impact on platelet activity.
- Results show that HSP47 localizes to the platelet-dense tubular system, mobilizes to the surface during activation, and enhances platelet adhesion and signaling by influencing GPVI dimerization.
