PLASMA EXPRESSION LEVELS OF MICRORNA-21 MIGHT HELP IN THE DETECTION OF HCV PATIENTS COMPLICATED BY HEPATOCELLULAR CARCINOMA.

Objective: To investigate the ability of the estimated plasma gene-expression levels of microRNA (miR)-21 and 126 to define patients suspected to have hepatocellular carcinoma (HCC) among patients with complicated hepatitis-C virus (HCV) infection.

Methods: Patients with uncomplicated (U-HCV) or complicated HCV underwent clinical and ultrasonographic (US) evaluations and assessment for the computerized hepatorenal index, hepatic steatosis index and fibrosis indices. Blood samples were obtained for estimation of serum levels of alpha-fetoprotein (AFP) and tumor necrosis factor-α (TNF-α), and plasma expression levels of miR-21 and miR-126 using the quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR).

Spontaneous Heterotopic Pregnancy: A Case Report of a Rare and Critical Obstetric Condition.

Heterotopic pregnancy is defined as the concurrent presence of both an intrauterine pregnancy and an extrauterine (typically ectopic) pregnancy. This report presents the case of a 36-year-old female patient who presented to the emergency department with lower abdominal pain. A comprehensive evaluation, including transabdominal and transvaginal ultrasound imaging, revealed a heterotopic pregnancy at an estimated gestational age of six weeks and two days.

Enhancing intraoral radiographic technique: introducing "Nallan's Lines".

Background: Intraoral radiography remains the most widely employed dental radiographic technique for producing geometrically accurate images with minimal distortion and magnification. Despite its common use in the dental office, incorrect projection geometry can be challenging leading to image distortions. To mitigate these inaccuracies specific radiographic landmarks on the face are utilized during periapical radiography.

Validation of energy valley optimization for adaptive fuzzy logic controller of DFIG-based wind turbines.

This study presents a novel optimization algorithm known as the Energy Valley Optimizer Approach (EVOA) designed to effectively develop six optimal adaptive fuzzy logic controllers (AFLCs) comprising 30 parameters for a grid-tied doubly fed induction generator (DFIG) utilized in wind power plants (WPP). The primary objective of implementing EVOA-based AFLCs is to maximize power extraction from the DFIG in wind energy applications while simultaneously improving dynamic response and minimizing errors during operation. The performance of the EVOA-based AFLCs is thoroughly investigated and benchmarked against alternative optimization techniques, specifically chaotic billiards optimization (C-BO), genetic algorithms (GA), and marine predator algorithm (MPA)-based optimal proportional-integral (PI) controllers.

Precision of Magnetic Resonance Imaging in Detection of Anterior Cruciate Ligament and Posterior Cruciate Ligament Ruptures and Subsequent Arthroscopic Correlations: An Investigation.

 The present study endeavors to scrutinize the precision of magnetic resonance imaging as a diagnostic modality for detecting ligament disruption of the knee, with arthroscopy serving as the gold standard. The study delves into the sensitivity, specificity, positive predictive value, and negative predictive value of magnetic resonance imaging (MRI) results in a cohort of 200 patients against diagnostic arthroscopy.  Our institution conducted a comprehensive clinical examination of all patients with knee injuries, and those with affirmative findings suggestive of ligament disruption were subjected to an MRI scan.

Investigating the Association Between Family Socioeconomic Profile and Diabetes Control in Children: A Cross-Sectional Study From Sudan.

Aims: Diabetes mellitus is the most common endocrine disease in childhood which significantly impacts quality of life, morbidity and mortality. This study aimed to investigate the socioeconomic background of children with diabetes and their families and to assess its association with diabetes control.

Methods: This cross-sectional study was conducted in Khartoum State, Sudan, in 2018, at three outpatient diabetes clinics, using standardised questionnaires.

Microbial Dynamics in Periodontal Regeneration: Understanding Microbiome Shifts and the Role of Antifouling and Bactericidal Materials: A Narrative Review.

Periodontal regeneration is a multifaceted therapeutic approach to restore the tooth-supporting structures lost due to periodontal diseases. This manuscript explores the intricate interactions between regenerative therapies and the oral microbiome, emphasizing the critical role of microbial balance in achieving long-term success. While guided tissue regeneration (GTR), bone grafting, and soft tissue grafting offer promising outcomes in terms of tissue regeneration, these procedures can inadvertently alter the oral microbial ecosystem, potentially leading to dysbiosis or pathogenic recolonization.

Oral antimicrobial options for vancomycin-resistant isolates in urine culture.

Objectives: The present study aimed to investigate the susceptibility profiles of vancomycin-resistant isolates in urine culture to create an antibiogram to guide selection of oral antimicrobials in British Columbia (BC), Canada.

Methods: An audit was conducted on all urine cultures reported from January 1, 2021, to December 31, 2023, in LifeLabs BC microbiology laboratories. species in urine were routinely tested with ampicillin, ciprofloxacin, nitrofurantoin, tetracycline, and vancomycin.

Outbreak of Meningitis in Iraq in 2023.

. To determine clinical presentations and laboratory findings of meningitis outbreak among children in 2023 in Iraq. .

Public health concern of antimicrobial resistance and virulence determinants in E. coli isolates from oysters in Egypt.

The emergence of critical-priority E. coli, carrying a wide array of resistance and virulence factors through food sources, poses a significant challenge to public health. This study aimed to investigate the potential role of oysters sold in Egypt as a source for E.

UPLC/HR-ESI-MS/MS and GC/MS profiling of Eriobotrya japonica L. fruit in correlation to its antioxidant, anti-inflammatory, and anti-arthritic effects.

Eriobotrya japonica Lindl. (Loquat) fruit is a subtropical edible fruit originally from China. It grows well in Egypt, but it is not widely known.

Computational insights of double perovskite NaCaCdH hydride alloy for hydrogen storage applications: a DFT investigation.

Prospective use of perovskite hydride materials in H storage a crucial element of clean energy systems has drawn a lot of attention. The structural, electrical, mechanical, thermodynamic, and H storage qualities of NaCaCdH hydride alloys were examined in this work using DFT. According to the structural properties, NaCaCdH has space group 225 (Fm3m), and optimized lattice parameters and volume of NaCaCdH are 3.

A New Fluorescent Method for Measuring Peroxiredoxin Enzyme Activity Using Monobromobimane.

A novel fluorometric method is presented for accurately quantifying peroxiredoxin (Prx) enzyme activity in vitro. The rate-limiting step in the Prx-catalyzed reaction is the dissociation of peroxide. To avoid interference from catalase, we developed an assay using tert-butyl hydroperoxide (t-BOOH) as a substrate for specific Prx activity measurement.

Gum Arabic as a potential candidate in quorum quenching and treatment of periodontal diseases.

Periodontal diseases are chronic inflammatory conditions influenced by bacterial biofilm formation and host immune responses, affecting millions worldwide. Traditional treatments like mechanical debridement and systemic antibiotics often face limitations, including biofilm resilience and antibiotic resistance. Gum Arabic (GA), a natural exudate from trees, presents a promising alternative with its anti-biofilm and anti-inflammatory properties.

Prevalence of breakthrough COVID-19 infection among healthcare workers in Baghdad.

Objective: To determine the prevalence and severity of breakthrough coronavirus disease-2019 infection among health workers, and to assess health workers' post-vaccination adherence to preventive guidelines.

Methods: The cross-sectional study was conducted from December 2021 to March 2022 at 2 major hospitals in Baghdad, Iraq, and comprised physicians, pharmacists, dentists and paramedical staff present at time of data collection. The participants were classified according to vaccination status with history of infection.

Association of BLK and BANK1 gene polymorphisms with systemic lupus erythematous in Egyptian patients.

This study examined the genotype, allelic frequencies (polymorphisms) in a sample of Egyptian patients and examined the relationship between disease activity in systemic lupus erythematosus (SLE) and the B lymphoid tyrosine kinase (BLK) and B-cell scaffold protein with ankyrin repeats 1 (BANK1) gene. This case control study involved 70 SLE patients and 40 subjects matched for age and sex as a control group. Clinical data were gathered from each participant, including SLE-related clinical activity indicators.

Search for Time-Dependent CP Violation in D^{0}→π^{+}π^{-}π^{0} Decays.

A measurement of time-dependent CP violation in D^{0}→π^{+}π^{-}π^{0} decays using a pp collision data sample collected by the LHCb experiment in 2012 and from 2015 to 2018, corresponding to an integrated luminosity of 7.7  fb^{-1}, is presented. The initial flavor of each D^{0} candidate is determined from the charge of the pion produced in the D^{*}(2010)^{+}→D^{0}π^{+} decay.