A 52-year-old woman with Charcot-Marie-Tooth disease presented with severe dyspnea due to bilateral diaphragmatic paralysis severely compromising respiratory function. There was little in the available literature to guide us regarding management of this unusual condition, and after deliberation, we decided to treat her with a staged plication of bilateral hemidiaphragms. Postoperatively, she demonstrated very good symptomatic relief supported by objective evidence, including improvement in lung function tests.
View Article and Find Full Text PDFObjective: To determine the frequency of symptomatic and asymptomatic peripheral arterial disease (PAD) in patients presenting with acute coronary syndrome (ACS) at a tertiary care center in Karachi.
Methods: A total of 350 consecutive patients presenting with ACS were recruited in this cross-sectional study. All patients were enrolled from the emergency department of the National Institute of Cardiovascular Diseases (NICVD), Karachi.