Granulomatous Pneumocystis jiroveci Pneumonia in a patient with chronic lymphocytic leukemia: a literature review and hypothesis on pathogenesis.

Background: Pneumocystis jiroveci pneumonia occurs frequently in patients with immunodeficiency syndromes, especially AIDS. Approximately 5% of AIDS patients have atypical granulomatous histology.

Case Report/methods: A 75-year-old woman with chronic lymphocytic leukemia was treated with alemtuzumab (campath-1H) 3 times weekly for 12 weeks.