An expeditious route to fluorinated rapamycin analogues by utilising mutasynthesis.

Rapamycin is a drug with several important clinical uses. Its complex structure means that total synthesis of this natural product and its analogues is demanding and lengthy. A more expeditious approach is to utilise biosynthesis to enable the generation of otherwise synthetically intractable analogues.

Rasagenthi lehyam (RL) a novel complementary and alternative medicine for prostate cancer.

Purpose: The use of complementary and alternative medicine (CAM) in cancer has been increasing. The therapeutic modalities which originated from India, viz., Ayurveda and Siddha, have phytotherapy as their fundamental basis and, therefore, produce few side effects.