Publications by authors named "Mohammed Mogharbel"
Background Hepatitis B Virus (HBV) continues to be a significant global health problem despite vaccination programs and effective antiviral drugs. Aim Assess tenofovir alafenamide fumarate (TAF) as a new treatment modality in light of the clinical characteristics of HBV patients. Settings and design A real-world observational study Methods and material We collected data of 71 HBV patients and recorded the hepatitis B virus deoxyribonucleic acid (HBV-DNA) plasma levels and biochemistry test results for the alanine aminotransferase (ALT), aspartate aminotransferase (AST), and serum creatinine levels at three time points, including baseline, time of switching to TAF, and six months after switching.
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- The study assessed the effectiveness and safety of an 8-week treatment with ledipasvir/sofosbuvir (LDV/SOF) in hepatitis C virus (HCV) genotype 4 patients in Saudi Arabia.
- Among 45 treatment-naïve, non-cirrhotic patients, the sustained virologic response 12 weeks post-treatment was 97.8%, indicating high efficacy.
- The treatment was generally well tolerated, with mild adverse effects reported, primarily headaches, and no serious complications noted.