Publications by authors named "Mohammed M Suleiman"

Article Synopsis
  • Pesticide exposure, specifically from Chlorpyriphos, causes significant reproductive issues in male rats by damaging their sex organs and reducing hormone levels, sperm quality, and testicular glycogen.
  • The study examined the effect of flavonoids (diosmin and hesperidin) on recovering reproductive functions in male Wistar rats after they were exposed to Chlorpyriphos for 60 days.
  • Results showed that the rats treated with flavonoids had notably better levels of reproductive hormones, improved sperm parameters, and higher testicular glycogen compared to those treated only with Chlorpyriphos, indicating the potential protective effects of these antioxidant compounds against pesticide toxicity.
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Alteration of redox status is one of the molecular pathways commonly associated with pesticide toxicity. Antioxidants, including those obtained from plant phenolics, have been shown to mitigate pesticide-induced cellular injury. The present study was aimed at evaluating the effect of daflon-500 , a flavonoid compound on sub-chronic chlorpyriphos-evoked changes in antioxidant and biochemical parameters in the hypophysis and testes of adult male rats.

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Background: African trypanosomiasis is a protozoan disease with huge socio-economic burden to sub-Saharan African exceeding US$4.6 annual loss. To mitigate the incidence of trypanosomal drug resistance, efforts are geared towards discovery of molecules, especially from natural products, with potential to inhibit important molecular target (trypanosome alternative oxidase, TAO) in trypanosomes that are critical to their survival.

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This study was to assess the anthelminthic potential of leaf extract against in experimentally infected broiler chickens. The extract and fractions were evaluated for in vitro inhibition and in vivo anthelmintic effects. Acute toxicity studies of extract revealed no sign of toxicity or death in birds at oral dose range of 1000-5000 and was considered safe.

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Helminthosis is one of the greatest causes of parasitic disease and loss in animal productivity. As such, the control of helminth parasites is of critical importance. This study was aimed to investigate the in vitro anthelmintic activity of G.

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Haemonchosis is a gastrointestinal parasitic disease of economic importance in ruminants especially sheep and goats. In view of the rising costs of conventional veterinary anthelmintics and the development of resistance by Haemonchus contortus, there is a need to develop alternative ethnoveterinary therapies for the treatment and management of Haemonchosis. This study investigated the anthelmintic activity of Dennettia tripetala G.

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Introduction: Trypanosomiasis is a neglected disease of humans and livestock caused by single-celled flagellated haemo-protozoan parasites belonging to the genus Trypanosoma.

Purpose: Widespread resistance to trypanocidal drugs creates urgent need for new, more effective drugs with potential to inhibit important trypanosome molecular targets.

Methods: Nine column chromatographic, partially purified leaf fractions of Azadirachta indica (AIF) were subjected to trypanosome alternative oxidase (TAO) inhibition assay using ubiquinol oxidase assay.

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Stomach ulcer is an endemic gastrointestinal disorder which constitutes a major public health problem all over the world. Stomach ulcer results when there is an imbalance between the protective factors (mucus and bicarbonate) and aggressive factors (acid and pepsin) in the stomach. Dried powdered leaves and stem of the phytomedicine () (1000 g) was extracted with methanol using a soxhlet apparatus.

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Ethnopharmacological Relevance: Pastoralists in Nigeria mix barks of Anogeissus leiocarpus (AL) Khaya senegalensis (KS) and potash (Pt) to treat animal African trypanosomosis.

Aim: To evaluate antitrypanosomal potential of A. leiocarpus, K.

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Due to the shortcomings associated with modern synthetic antidiarrhoeal drugs, it is important to find newer, safer and cheaper antidiarrhoeal agents from natural sources. The study was conducted to evaluate the anti-diarrhoeal activity of the fractions of the stem-bark of in laboratory animal models. The effect of different concentrations (1.

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The aim of this study was to investigate the ameliorative effect of Linn used traditionally against trypanosomosis. Twenty-five adult Wistar rats of both sex were individually infected intraperitoneally (IP) with 10 per ml of blood. Following establishment of infection, the rats were randomly divided into five groups of 5 rats each.

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Stylophora pistillata is a widely used coral "lab-rat" species with highly variable morphology and a broad biogeographic range (Red Sea to western central Pacific). Here we show, by analysing Cytochorme Oxidase I sequences, from 241 samples across this range, that this taxon in fact comprises four deeply divergent clades corresponding to the Pacific-Western Australia, Chagos-Madagascar-South Africa, Gulf of Aden-Zanzibar-Madagascar, and Red Sea-Persian/Arabian Gulf-Kenya. On the basis of the fossil record of Stylophora, these four clades diverged from one another 51.

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Background: The poultry industry due to intensive methods of farming is burdened with losses from numerous infectious agents, of which one is the fungus Aspergillus fumigatus. In a preliminary study, the extracts of Loxostylis alata A. Spreng, ex Rchb.

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The coconut crab (Birgus latro), an endangered marine-dispersed crustacean, is facing severe and probably accelerating population extinction worldwide, but biological information on its conservation remains deficient. In order to reveal the genetic structure of B. latro, 10 microsatellite loci were developed.

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Synopsis of recent research by authors named "Mohammed M Suleiman"

  • Mohammed M Suleiman's recent research primarily focuses on the assessment of natural compounds, particularly flavonoids and plant extracts, for their protective effects against pesticide-induced reproductive and oxidative damage in animal models.
  • The studies reveal that micronized purified fractions of diosmin and hesperidin, as well as daflon-500, effectively mitigate the harmful effects of chlorpyriphos, suggesting a promising therapeutic role for these flavonoids in reproductive health.
  • Additionally, his work explores the anthelmintic activity of various plant extracts against parasitic infections like trypanosomiasis and helminthosis, emphasizing the potential of natural remedies in veterinary and agricultural health management.

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