Effect of human chorionic gonadotrophin on in vitro contractions of stimulated detrusor muscle strips of female rats.

Aims: We studied the effect of human chorionic gonadotrophin (hCG) on the in vitro detrusor muscle contractions in female rats.

Methods: Two adjacent detrusor muscle strips from the bladder dome of 18 female Wistar rats (230-250 gm) were mounted in an organ bath for the recording of isometric tension. Carbachol (10(-9)-10(-3) M), alpha,beta methylene adenosine 5'-triphosphate (ATP) (10(-9)-10(-3) M) and potassium chloride (KCl) (10(-4)-10(-3) M) were applied (n = 6 x 3 groups).