The combined effect of essential oils on wood physico-chemical properties and their antiadhesive activity against mold fungi: application of mixture design methodology.

In the heritage field, the microbial adhesion on wood, and consequently the formation of biofilm led to inestimable losses of historical and cultural monuments. Thereby, this study aimed to examine the combined effect of and essential oils on wood surface physico-chemical properties, and to elaborate the optimal mixture using the mixture design approach coupled to the contact angle method. It was found that both wood hydrophobicity and electron donor character increased significantly after treatment using an optimal mixture containing 57% and 43% of and essential oils, respectively.

Gamma-irradiation effect on the chemical composition and antibacterial activity of the moroccan L. essential oil.

The primary objective of the present inquiry was to assess the impact of gamma irradiation on the chemical composition and antibacterial potential of the essential oil extracted from the aerial parts of Moroccan L. to this end, two distinct irradiation doses of 5 kGy and 10 kGy were administered to the essential oil, and the resultant effects were evaluated via analysis of the oil's chemical composition and antibacterial activity. The study findings have revealed that irradiation technology possesses the remarkable ability to modulate the concentrations of specific chemical constituents in a manner that effectively amplifies the antibacterial activity of the essential oil.

Anti-adhesive activity of some secondary metabolites against Staphylococcus aureus on 3D printing medical materials.

Recent improvements in 3D printing technology have increased the usage of 3D printed materials in several areas. An exciting and emerging area of applying these next-generation manufacturing strategies is the development of devices for biomedical applications. The main aim of this work was to investigate the effect of tannic acid, gallic acid, and epicatechin gallate on the physicochemical characteristics of acrylonitrile butadiene-styrene (ABS) and Nylon 3D printing materials using the contact angle method.

The theoretical adhesion of Staphylococcus aureus and Pseudomonas aeruginosa as nosocomial pathogens on 3D printing filament materials.

Microbial infections and nosocomial diseases associated with biomaterial have become a major problem of public health and largely lead to revision surgery, which is painful and quite expensive for patients. These infections are caused by formation of biofilm, which present a difficulty of treatment with conventional antibiotics. The aim of our study is to investigate the theoretical adhesion of Staphylococcus aureus and Pseudomonas aeruginosa on four 3-dimensional printing filament materials used in the manufacture of medical equipment.

Carob Seed Peels Effect on Cognitive Impairment and Oxidative Stress Status in Methionine-Induced Mice Models of Schizophrenia.

(Carob tree) is a Mediterranean evergreen, well known for its medicinal properties. The different parts of Carob were proven to exert antidiabetic, antibacterial, antifungal, and antiproliferative effects. Hence, the present paper aims to validate the positive correlation between the high antioxidant activity of carob seed peels and the improvement of negative symptoms of schizophrenia.

Non-volatile constituents from Monimiaceae, Siparunaceae and Atherospermataceae plant species and their bioactivities: An up-date covering 2000-2021.

The Monimiaceae, Siparunaceae, and Atherospermataceae, formerly included in the broad ''old'' Monimiaceae family, have long been known for their uses in traditional medicine and have proven to be rich sources of chemically diverse specialized metabolites with numerous potent biological and therapeutical properties. The progress made recently has expanded their phytochemistry and pharmacology albeit to different extents. This review focuses on the non-volatile constituents isolated from the three plant families during the last two decades and their emerging therapeutic potential.

The Effect of Different Vegetable Oils on Cedar Wood Surface Energy: Theoretical and Experimental Fungal Adhesion.

Despite having been used for ages to preserve wood against several effects (biological attack and moisture effects) that cause its degradation, the effect of vegetable oils on the cedar wood physicochemical properties is poorly known. Thus, in this study, the hydrophobicity, electron-acceptor ( ), and electron-donor ( ) properties of cedar wood before and after treatment with vegetable oils have been determined using contact angle measurement. The cedar wood has kept its hydrophobic character after treatment with the different vegetable oils.

Phytochemistry, bioactivity: suggestion of Ceratonia siliqua L. as neurodegenerative disease therapy.

Carob tree (Ceratonia siliqua L.) is one of the most widespread medicinal plants in the Mediterranean area. Traditionally, it was cultivated for its ethnopharmacological benefits and, more especially, for the seeds, which served as unit of measurement of jewelers "carat.

Dinuclear Cyclam Complex as a Non-Cytotoxic, Anti-Hyperurecemic Lead: In vitro to In vivo Studies.

Background: Uric acid is the end product of purine metabolism in humans and its increased level in serum leads to hyperuricemia. Among the different regulatory factors to control the level of uric acid in humans, xanthine oxidase (XO) is a well-established pharmacological target, as it is directly involved in uric acid production.

Methods: The aim of the study was to present a systematic approach to analyze the xanthine oxidase inhibition studies from in vitro leading to in vivo.

HPLC and GC-MS Analysis of Tunisian Peganum harmala Seeds Oil and Evaluation of Some Biological Activities.

In this work, we characterized by high-performance liquid chromatography, the γ-tocopherol (573.66 μg/g), and by gas chromatography-mass spectrometry, the linoleic acid (62.05%) as major components from Peganum harmala L.

Di-hydro-cyclam dimaleate [H2(cyclam)(maleate)2].

The asymmetric unit of the title mol-ecular salt [systematic name: 1,4,8,11-tetraazacyclotetradecane-1,8-diium bis(3-carboxy-prop-2-enoate)], C10H26N4 (2+)·2C4H3O4 (-), contains two half-cations (both completed by crystallographic inversion symmetry) and two maleate anions. The cyclam macrocycles adopt trans-III conformations, supported by two intra-molecular N-H⋯O hydrogen bonds. The O-bonded H atom of each maleate ion is disordered over two positions with an occupancy ratio of 0.

Structural bases of oxygen-sensitivity in Fe(II) complexes with tripodal ligands. Steric effects, Lewis acidity and the role of ancillary ligands.

The complexation of Fe(SO(3)CF(3))(2) to the series of fluoro α-substituted tris-(2-aminomethylpyridyl)amine tripods F(1-3)TPA yields the triflato F(1-3)TPAFe(SO(3)CF(3))(2) complexes which have firstly been characterized in solution. As expected, bis-acetonitrile charged species are present in CH(3)CN, and neutral bis-triflato complexes in CH(2)Cl(2). The X-ray diffraction analyses of F(1)TPAFe(SO(3)CF(3))(2) and F(2)TPAFe(SO(3)CF(3))(2) crystallized from CH(2)Cl(2) solutions show that their structure in solution is retained in the solid state, with coordination of both triflate ions and the κ(4) coordination mode of the tripod in each complex.

Ortho-rhom-bic polymorph of (6,7-dimeth-oxy-1,2,3,4-tetra-hydro-isoquinolin-1-yl)methanol.

The asymmetric unit of the title compound, C(12)H(17)NO(3), contains two mol-ecules with different conformations. It is a polymorph of the monoclinic form [El Antri et al. (2004 ▶).

Unprecedented incorporation of α-emitter radioisotope 213Bi into porphyrin chelates with reference to a daughter isotope mediated assistance mechanism.

For the first time, α-emitter radioisotope (213)Bi has been incorporated into porphyrin chelates, with rates matching with the short period of the radionuclide. An in situ transmetalation mechanism involving the daughter isotope (209)Pb is expected to boost the (213)Bi radiolabeling process.

Efficient photoinduced electron transfer in a porphyrin tripod-fullerene supramolecular complex via pi-pi interactions in nonpolar media.

A novel porphyrin tripod (TPZn(3)) was synthesized via "click chemistry". Three porphyrin moieties of TPZn(3) are geometrically close and linked by a flexible linker. The electron-transfer oxidation of TPZn(3) results in intramolecular pi-dimer formation between porphyrin moieties as indicated by electrochemical, vis-NIR, and ESR measurements.

Reinvestigation of 4-methyl-anilinium dihydrogen phosphite.

The crystal structure of the title compound, C(7)H(10)N(+)·H(2)PO(3) (-), has been reported previously by Sabounchei & Naghipour [Asian J. Chem. (2003) ▶, 15, 1677-1686].

Regiospecific intramolecular O-demethylation of the ligand by action of molecular dioxygen on a ferrous complex: versatile coordination chemistry of dioxygen in FeCl(2) complexes with (2,3-dimethoxyphenyl) alpha-substituted tripods in the tris(2-pyridylmethyl)amine series.

We report in this article one of the first examples of a reaction of O-demethylation carried out at a Fe(II) center by molecular dioxygen, in the homogeneous phase in non-porphyrinic chemistry. This reaction parallels at the intramolecular level a very important process found in biology leading to the derivatization and elimination of drugs by oxygen-dependent enzymes that contain nonheme iron centers. To get insight into some reactivity aspects of this reaction, we have used dioxygen and iron complexes coordinated to ligands that are substituted by methoxy groups.

Coordination of bismuth and lead in porphyrins: towards an in-situ generator for alpha-radiotherapy?

In order to investigate the possible coordination of both bismuth(III) and lead(II) by porphyrins for an application in alpha-radioimmunotherapy, several series of functionalized bismuth porphyrins have been synthesized and their stabilities in acidic medium were compared. Where unfunctionalized porphyrins are not suitable for such a purpose, strapped hanging carboxylate porphyrins are stable and allow a rapid coordination of both bismuth and lead. This property could lead to the preparation of an in-situ generator of alpha particles by a pre-complexation of (212)lead, the radioactive parent of (212)bismuth, in the ligand.

Dilead(II) hydrogen-phosphite dinitrate.

In the title compound, Pb(2)(HPO(3))(NO(3))(2), the two distinct Pb(2+) ions (both with site symmetry m) adopt irregular PbO(10) coordination polyhedra. The structure is completed by two distinct nitrate groups (in which one O atom and the N atom have m site symmetry for both ions) and an HPO(3) (2-) anion (in which one O atom and the P and H atoms have m site symmetry). The connectivity of the PbO(10), NO(3) and HPO(3) units in the crystal structure results in a three-dimensional network.

The preparation and full characterization of dichloroferrous complexes of mono-, bis- and tris-alpha-methyl substituted tris(2-pyridylmethyl)amine (TPA) ligands. Structural bases of stability of the complexes in solution.

Reaction of FeCl(2) with the mono-, bis- and tris-alpha-methyl substituted tripods of tris(2-pyridylmethyl)amine (TPA) structure (L(1-3)) affords stable complexes that have been fully characterized in solid state and in solution. Whereas L(1) and L(2) coordinate in the tetradentate mode yielding complexes with pseudo-octahedral geometry, L(3) adopts the hypodentate coordination mode with one dangling pyridine, providing a trigonal bipyramidal environment around the metal. Instead of lowering the redox potential, methyl substitution increases the Fe((II))/Fe((III)) value.

Reactivity of molecular dioxygen towards a series of isostructural dichloroiron(III) complexes with tripodal tetraamine ligands: general access to mu-oxodiiron(III) complexes and effect of alpha-fluorination on the reaction kinetics.

We have synthesized the mono, di-, and tri-alpha-fluoro ligands in the tris(2-pyridylmethyl)amine (TPA) series, namely, FTPA, F(2)TPA and F(3)TPA, respectively. Fluorination at the alpha-position of these nitrogen-containing tripods shifts the oxidation potential of the ligand by 45-70 mV per added fluorine atom. The crystal structures of the dichloroiron(II) complexes with FTPA and F(2)TPA reveal that the iron center lies in a distorted octahedral geometry comparable to that already found in TPAFeCl(2).

Dicaesium magnesium bis-(dihydrogen phosphate(V)) dihydrate.

The title compound, Cs(2)Mg(H(2)P(2)O(7))(2)·2H(2)O, is isostructural with the related known isoformular phosphates. The crystal framework consists of corner-sharing MgO(6) and H(2)P(2)O(7) polyhedra, leading to tunnels parallel to the b-axis direction in which Cs(+) ions are located. The H(2)P(2)O(7) unit shows a bent eclipsed conformation.

Isolation and X-ray crystal structure of tetrahydroisoquinoline alkaloids from Calycotome villosa Subsp. intermedias.

Two tetrahydroisoquinoline alkaloids were extracted from the alkaloid fraction of a methanol extract of the seeds of Calycotome Villosa Subsp. intermedia. Their structures were established as (R)-1-hydroxymethyl-7-8-dimethoxy-1,2,3,4-tetrahydro- isoquinoline (1) and (S)-7-hydroxymethyl-2-3-dimethoxy-7,8,9,10-tetrahydroisoquinoline chloride (2) by spectroscopic techniques and X-ray diffraction analysis.

Flavone glycosides from Calycotome villosa Subsp. Intermedia.

The known flavonoid chrysin-7-O-(beta-D-glycopyranoside) (chrysin glucoside,1) as a major fraction and a new glycoside flavone, chrysin-7-O-beta-D-[(6"-acetyl)glycopyranoside] (2) were isolated from the flowers and leaves of Calycotome Villosa Subsp. Intermedia, They were identified by UV-Vis, 1R, (1)H-, (13)C-NMR and ESI-MS.

Coordination and structural studies of crowned-porphyrins.

Simple chelating agents have been synthesized using a porphyrin and a covalently linked crown-ether. Depending on the relative spatial arrangement of both motifs, the resulting ligands, either a macrotricycle or bis-macrocycles, differ one from another by their flexibility or their aptitude to chelate bivalent or trivalent cations. The coordination chemistry as well as the structural study of these ligands and complexes are reported.