Neutrophil-to-Lymphocyte Ratio as a Potential Biomarker to Managing Type 2 Diabetes Mellitus and Predicting Disease Progression.

Introduction Diabetes is a chronic disease that causes dysregulation of blood glucose. Type 2 diabetes mellitus (T2DM) could result in long-term inflammatory conditions that affect different organs of the body. Despite the availability of diagnostic markers like glycated hemoglobin (HbA1c) for T2DM, it is essential to find an appropriate marker that could predict long-term complications.

Evaluation of a Rapid Urine Antigen Detection Assay as a Point-of-Care Test in the Diagnosis of Community-Acquired Pneumonia.

Introduction Community-acquired pneumonia (CAP) is among the most common public health problems encountered throughout the world. CAP is a frequent cause of lower respiratory tract infections among children and geriatric-age persons. The etiology of CAP is complex but generally involves infection with bacteria like  (.

Surgical Treatment of Propriospinal Myoclonus: A Case Report.

Propriospinal myoclonus (PSM) is a rare segmental movement disorder characterized by repetitive irregular myoclonic jerks of the trunk and/or axial limbs at the resting state. It is imperative to make a correct diagnosis as other movement disorders can be mistaken for or mask PSM. Therefore, a battery of neuroimaging and neurophysiological testing must be undertaken.

Artificial Intelligence for Colonoscopy: Past, Present, and Future.

During the past decades, many automated image analysis methods have been developed for colonoscopy. Real-time implementation of the most promising methods during colonoscopy has been tested in clinical trials, including several recent multi-center studies. All trials have shown results that may contribute to prevention of colorectal cancer.

Bioinformatics analysis integrating metabolomics of mA RNA microarray in intervertebral disc degeneration.

To explore the potential functions and mechanism of .methyladenosine (mA) abnormality of RNAs in nucleus pulposus from the intervertebral disc degeneration (IDD). We performed rat model, mA epitranscriptomic microarray, bioinformatics analysis and metabolomics.

Size Matters: Which Adolescent Patients Are Most Likely to Require Surgical Decompression for Lumbar Disk Herniations?

Background: Lumbar herniated nucleus pulposis (HNP) occurs infrequently in the pediatric/adolescent population. A minority of patients with radicular symptoms fail to improve with conservative management and require discectomy. The authors hypothesize that children who ultimately require surgical intervention have an underlying lumbar stenosis predisposing them to continued symptoms.

Magnetic Resonance Neurography of the Lumbosacral Plexus in Failed Back Surgery Syndrome.

Study Design: Retrospective clinical case series.

Objective: To study the role of magnetic resonance neurography (MRN) of the lumbosacral plexus in management of patients with failed back surgery syndrome (FBSS).

Summary Of Background Data: FBSS is one of the major problems in health care, affecting up to 40% of patients after spine surgery.

The naloxone option.

This quick guide provides you with naloxone dosing information and steps you'll want to take once the crisis has passed.

Magnetic Resonance Neurography in Chronic Lumbosacral and Pelvic Pain: Diagnostic and Management Impact-Institutional Audit.

Background/objective: Low back and pelvic pain are among the most prevalent conditions worldwide, with major social and economic costs. The aim of this study was to evaluate the role of magnetic resonance neurography (MRN) of lumbosacral plexus in the management and outcomes of these patients with chronic pain.

Methods: Consecutive patients with chronic lumbosacral and pelvic pain referred for MRN over a year were included.

Defining Avoidable and Unavoidable Complications in Spine Surgery: A Survey-based Study of Spine Fellowship Directors.

Study Design: A cross-sectional survey of orthopedic spine surgery fellowship directors in the United States.

Objective: The aim of this study was to investigate whether consensus exists with respect to spine-related adverse events and certain hospital-acquired conditions (HACs) or "never events."

Summary Of Background Data: As part of a broad effort to improve health care outcomes, providers are no longer reimbursed for HACs, which are deemed avoidable.

Computed tomography-guided sub-end plate injection of pingyangmycin for a novel rabbit model of slowly progressive disc degeneration.

Background Context: Different animal models are used in disc degenerative disease research by now. To our knowledge, a functional animal model that mimics ischemic and slowly progressive disc degeneration of humans does not exist.

Study Design: This is an experimental animal study of disc degeneration.

The effect of high obesity on outcomes of treatment for lumbar spinal conditions: subgroup analysis of the spine patient outcomes research trial.

Study Design: Spine Patient Outcomes Research Trial subgroup analysis.

Objective: To evaluate the effect of high obesity on management of lumbar spinal stenosis, degenerative spondylolisthesis (DS), and intervertebral disc herniation (IDH).

Summary Of Background Data: Prior Spine Patient Outcomes Research Trial analyses compared nonobese and obese patients.

Effect of psychopathology on patient-perceived outcomes of total knee arthroplasty within an indigent population.

Background: Factors other than surgical technique and implants impact patient outcomes following a total knee arthroplasty. The purpose of this study was to analyze the effects of psychopathology on the rate of improvement following total knee arthroplasty in an indigent population.

Methods: One hundred and fifty-four consecutive indigent patients undergoing a primary total knee arthroplasty for arthritis were enrolled and available for follow-up.

Psychosocial profiles of indigent patients with severe osteoarthritis requiring arthroplasty.

This study documents the prevalence of Axis I diagnoses (ie, depression, anxiety, and others) and their effects on preoperative pain, disability, function, and quality of life assessments in an indigent population undergoing total joint arthroplasty. Consecutive indigent patients scheduled for total joint arthroplasty were categorized by psychosocial testing as either psychologically distressed (PD) or nonpsychologically distressed. Of the subjects, 38% were found to be psychologically distressed.

Vertebroplasty and kyphoplasty.

Vertebral compression fractures occur more frequently than hip and ankle fractures combined. These fragility fractures frequently result in both acute and chronic pain, but more importantly are a source of increased morbidity and possibly mortality. Percutaneous veretebral augmentation offers a minimally invasive approach for the treatment of vertebral compression fractures.

Effect of kyphoplasty on survival after vertebral compression fractures.

Background: A growing population of patients with osteoporosis and fragility fractures has developed. Fragility fractures, including vertebral compression fractures, have been associated with increased mortality. Early operative interventions for patients sustaining hip fractures have been found to reduce mortality.

Vertebroplasty and kyphoplasty.

Vertebral compression fractures occur more frequently than hip and ankle fractures combined. These fragility fractures frequently result in both acute and chronic pain, but more importantly are a source of increased morbidity and possibly mortality. Percutaneous vertebral augmentation offers a minimally invasive approach for the treatment of vertebral compression fractures.