Publications by authors named "Mohammed J Al Yasiri"
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Synopsis of recent research by authors named "Mohammed J Al Yasiri"
- Mohammed J Al Yasiri's recent research concentrates on the development of targeted inhibitors for key enzymes involved in crucial biological pathways, particularly focusing on the NF-κB-inducing kinase (NIK) relevant to cancer treatment.
- His notable work identifies an alkynylpyrimidine-based covalent inhibitor that specifically targets a unique cysteine residue in NIK, which is a significant discovery given that selective inhibitors are essential for effective drug development.
- The findings, published in the Journal of Medicinal Chemistry, emphasize the importance of understanding enzyme structures for the design of potent and selective pharmacological agents, which could ultimately lead to advances in therapeutic strategies for diseases like cancer.
