Silent brain infarctions in patients with rheumatic mitral stenosis.

Background: Silent brain infarctions (SBI) are commonly detected in brain imaging. The association of SBI with rheumatic mitral stenosis (MS) is not clearly relevant. Based on magnetic resonance imaging, we aimed to describe the prevalence of SBI in patients with rheumatic MS and the cardiac abnormalities related to their occurrence.

A systematic review of the impact of therapeutic education programs on the quality of life of people with Multiple Sclerosis.

Background: Faced with a deemed mediocre quality of life (QoL) in people with multiple sclerosis (pwMS), the effectiveness of therapeutic education (TPE) programs is called into question. This systematic review is conducted to examine the impact of the TPE programs on the QoL of pwMS.

Methods: A search was performed in three databases (PubMed, Web of Science and Scopus) to identify relevant studies published between 2007 and 2022.

[Thrombolysis alert in ischemic stroke: experience of the international private clinic Al Badie in Fez (cross-sectional study of 60 cases)].

Intravenous thrombolysis is the standard treatment for acute ischemic stroke. We here report the cases of thrombolysis alert in the private sector in Morocco We conducted a prospective study of all patients with neurological deficit of sudden onset occurred within the first 12 hours admitted to the Emergency Department of the Al Badie international private clinic from January 2022 to September 2023. Epidemiological, clinical and etiological characteristics as well as data on outpatient and inpatient delays were collected.

Silent brain infarctions in patients with acute cardioembolic stroke.

Introduction And Aim: The advances and the wide use of brain imaging have considerably increased the prevalence of silent brain infarctions (SBI). We aim in this study to determine the prevalence of SBI in patients presenting with acute cardioembolic stroke and the predictive cardiovascular risk factors.

Methods: This retrospective study included 267 patients presenting with acute cardioembolic stroke in the emergency and/or neurology departments of the Hassan II University Hospital Center.

Phenotype and molecular characterization of Wilson's disease in Morocco.

Background And Study Aims: In Morocco the prevalence of Wilson disease (WD) and the spectrum of mutations are not known. The aim of the present study was to estimate the prevalence of WD in Morocco, to evaluate the phenotype among a large cohort of WD patients, and to characterize ATP7B variants in a subgroup of WD patients.

Patients And Methods: We collected data from 226 patients admitted to five university hospital centers in Morocco between 2008 and 2020.

Knowledge, attitudes, and practices of the ethics in medical research among Moroccan interns and resident physicians.

Background: In Morocco, medical research ethics training was integrated into the medical curriculum during the 2015 reform. In the same year, a law on medical research ethics was enacted to protect individuals participating in medical research. These improvements, whether in the reform or in the enactment of the law, could positively impact the knowledge of these researchers and, consequently, their attitudes and practices regarding medical research ethics.

Stroke services in MENA: What is there and what is needed.

Objectives: Stroke represents a health care challenge to most parts of the world including the Middle East and North Africa (MENA) region. The MENA represents 6% of the world population with an age-standardized stroke rate of 87.7 (78.

The Moroccan Arabic Bedside Western Aphasia Battery-Revised: Linguistic and Psychometric Properties.

Purpose: The objectives of this study were (a) to linguistically and culturally adapt the English bedside version of the Western Aphasia Battery-Revised (Bedside WAB-R) into Moroccan Arabic (MA) and (b) to assess its psychometric properties.

Method: The Bedside MA-WAB-R was piloted on a population of 20 participants after a process of linguistic adaptation from English to MA. To verify the psychometric properties of the test, a group of healthy controls ( = 106) and a group of persons with chronic aphasia ( = 52) completed the Bedside MA-WAB-R.

Intracranial hypertension with reversible cerebral edema: Atypical presentation of neuropsychiatric systemic lupus erythematosus.

We described in this article a 19-year-old girl with an intracranial hypertension as an initial presentation of neuropsychiatric lupus. The brain MRI showed diffuse, bilateral and symmetrical white and grey matter hyperintensities. These lesions completely disappeared after 3 months of treatment.

Stroke services in Africa: What is there and what is needed.

Background: Over the past few years, the incidence and prevalence of stroke has been rising in most African countries and has been reported as one of the leading causes of morbidity and mortality. To study this problem, we need to realize the quality and availability of stroke care services as a priori to improve them.

Methods And Results: In this study, we investigated the availability of different stroke-related services in 17 countries from different African regions.

Pulmonary and intracranial miliary tuberculosis secondary to Behçet's anti-TNF alfa treatment.

Behçet disease is a rare vasculitis that affects vessels of different body parts, causing different kinds of manifestations. We report a case of a 47 years old woman who had a tumor necrosis factor alfa blocker prescription due to a Behçet's disease relapse. The patient then developed a cerebral and pulmonary tuberculous miliary due to immunodeficiency.

Stroke Mimics: Experience of a Moroccan Stroke Unit.

Background: Stroke mimic is a medical condition presenting with acute neurological deficit and simulate real stroke. The objective of this study was to evaluate the frequency and the various etiologies of stroke mimics in our center.

Methods: We retrospectively reviewed the Thrombolysis Alert registry and we studied the frequency and characteristics of patients with stroke mimic.

Limbic encephalitis: Experience of a moroccan center.

Objectives: Histologically defined as an inflammation-degeneration of limbic structures, limbic encephalitis (LE) is a rare disease and often difficult to diagnose particularly in institutions with limited access to laboratory tests such as antineuronal antibodies or HSV-PCR, and functional imaging. We aimed to describe the demographic, clinical, paraclinical, and etiological features of LE, as well as its medium-term prognosis in Moroccan patients.

Materials And Methods: We collected retrospectively all patients diagnosed with LE in the Department of Neurology of the University Hospital Hassan II of Fez (Morocco) between September 2008 and December 2016.

Intravenous thrombolysis with rt-PA in stroke: experience of the moroccan stroke unit.

The majority of strokes are due to blockage of an artery in the brain by a blood clot. Prompt treatment with thrombolytic drugs can restore blood flow before major brain damage has occurred. We report the case series of all patients who were treated with rt-PA at Stroke Unit of HASSAN II University hospital between 2010 and 2013.

Psychiatric disorders revealing multiple sclerosis after 20 years of evolvement.

Previous research indicates that the onset of psychiatric disorders is sometimes associated with multiple sclerosis (MS) evolving several years later. However, information on why this might occur, and on the outcomes of such patients, is still lacking. We aim to discuss these limitations with the current paper.

Syphilitic limbic encephalitis revealed by status epilepticus.

Limbic encephalitis (LE) is an inflammatory disorder of the limbic system; the clinical features are diverse, characterised by the development of neuropsychiatric symptoms, its aetiologies are various; syphilis is a rare entity. We report the case of a 50-year-old-man with syphilitic LE revealed by an inaugural status epilepticus. Diagnosis was made considering clinical, biological and radiological arguments.