Publications by authors named "Mohammed F Abosamak"
Unlabelled: The diuretic effect of the combined furosemide and aminophylline/theophylline among pediatric patients remains unclear. The primary aim of this systematic review was to examine the clinical diuretic effects (urine output and fluid balance) of co-administration of furosemide and aminophylline/theophylline as compared to furosemide alone in pediatric population. Ovid MEDLINE, CENTRAL, and EMBASE were searched from its inception until March 2022 for observational studies and randomized controlled trials (RCTs) comparing the administration of furosemide versus furosemide and aminophylline/theophylline in pediatric population.
View Article and Find Full Text PDFBackground And Aims: Avoidance of general anaesthesia for short-duration surgeries is a prerequisite, especially for children. Spinal anaesthesia is established as an appropriate anaesthetic procedure for this target. Midazolam has been proven to be safe for children as premedication.
View Article and Find Full Text PDFArticle Synopsis
- Venous thromboembolism (VTE) is a serious condition that includes deep vein thrombosis (DVT) and pulmonary embolism (PE), with a recurrence rate of about 25% over five years, and individual genetic risk profiling may help predict this recurrence.
- This study aimed to evaluate the effects of common prothrombotic genetic variations on the likelihood of VTE recurrence in patients who were recently diagnosed with unprovoked cases.
- The findings revealed that patients with three or more genetic risk alleles had a significantly higher risk of recurring VTE compared to those with fewer alleles, indicating that a Genetic Risk Score (GRS) model can be a valuable tool for risk assessment in VTE patients.
Article Synopsis
- The study reviewed the impact of positioning (prone vs. supine) on oxygen levels in COVID-19 patients, highlighting that the prone position significantly improved the PaO₂/FiO₂ ratio and SpO₂.
- Thirty-five non-randomized trials, involving 1712 patients, were analyzed, showing that while prone positioning reduced mortality rates, it did not significantly affect the intubation rate.
- The authors concluded that although prone positioning benefits oxygenation, more extensive and standardized research is needed to enhance evidence reliability.
Alterations in the lipid profile associate with a dysregulated inflammatory, prothrombotic, anti-fibrinolytic state and development of severe acute kidney injury in coronavirus disease 2019 (COVID-19): A study from Cincinnati, USA.
Diabetes Metab Syndr
June 2021
Background And Aims: Reduction of atherogenic lipoproteins is often the ultimate goal of nutritional interventions, however this is complicated given that hypolipidemia is frequently observed in coronavirus disease 2019 (COVID-19) patients. We aimed to explore the association of hypolipidemia with patient outcomes in terms of immunothrombosis and multiorgan injury, focusing on specialized apolipoproteins apo A1 and apo B.
Methods: Lipid profiles of 50 COVID-19 patients and 30 sick controls presenting to the Emergency Department (ED) were measured in this prospective observational study.