A Study of VEGF Gene Polymorphism in Egyptian Patients with Diabetic Retinopathy.

Background: There are subgroups of patients with diabetes mellitus (DM) in whom diabetic retinopathy (DR) does not develop despite poor long-term control of their disease, while others exercising fairly good control, develop retinopathy. So, we aimed to investigate the association of DR with -2578 polymorphism of the vascular endothelial growth factor (VEGF) gene, which has been reported to be associated with increased VEGF production, in Egyptian diabetic patients.

Materials And Methods: This is a case control study in which 148 diabetic patients were enrolled.