Background: Infective endocarditis (IE) caused by non-HACEK gram-negative bacteria (nHGNB) is uncommon. In the 2023 Duke-ISCVID diagnostic criteria, and were added as "typical" pathogens. We examine the consequences of this addition, the risk of IE in bacteremia from nHGNB species, and the features of IE caused by nHGNB.
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