Publications by authors named "Mohammed Bin-Mahfooz"
Background: The potential link between disease-modifying therapies (DMTs) and malignancy in multiple sclerosis (MS) patients has generated significant concern, particularly given the immunosuppressive nature of these treatments. Conflicting evidence in the literature has left this issue unresolved, underscoring the need for definitive research to inform clinical practice. This study addresses this gap by examining cancer occurrence among MS patients on DMTs treated at two tertiary-care centers in Saudi Arabia.
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- Traumatic brain injury (TBI) is a major global health issue, often resulting in serious health complications, and there is growing evidence of the immune system's role in TBI's effects.
- This systematic review and meta-analysis aimed to evaluate the safety and effectiveness of new immunomodulatory therapies for TBI by reviewing multiple studies, including randomized controlled trials (RCTs).
- While most therapies did not significantly change overall mortality rates, the study found that erythropoietin (EPO) notably reduced mortality, and adverse events were comparable to control groups.
Background: Incidence and outcomes of acute kidney injury (AKI) among neonates who underwent open-heart surgery are not well highlighted in the literature. We aim to assess the incidence, risk factors, and outcome of AKI among neonates undergoing open-heart surgery.
Methods: This is a retrospective cohort study between 2016 and 2021 for all neonates requiring open heart surgery.
Background: Ganglioneuroma (GN) is a rare, benign tumor that originates from neural crest cells and can potentially affect any anatomical site within the sympathetic nervous system. Typically, GNs are more frequently reported in children and young adults, with a slightly higher prevalence in females. We are reporting a rare case of a giant lumbar spine ganglioneuroma by outlining the clinical presentation, radiological finding, management, and outcome.
View Article and Find Full Text PDFBackground: The use of Alteplase (ALT) bridging to endovascular mechanical thrombectomy (MT) has become the standard approach in treating patients with large vessel stroke (LVO). Tenecteplase (TNK) has emerged as an equivalent fibrinolytic agent in treating ischemic stroke due to its remarkable pharmacological characteristics. This study aims to compare the use of intravenous TNK to ALT bridging to MT in patients with LVO.
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