Use of intraoperative mild hyperventilation to decrease the incidence of postoperative shoulder pain after laparoscopic gastric sleeve surgery: A prospective randomised controlled study.

Background And Aims: Post-laparoscopic shoulder pain (PLSP) is a common problem. It is a referred type of pain resulting from irritation of phrenic nerve endings. Multiple manoeuvres were used to decrease its incidence with varying success rates.

High levels of leptin and non-high molecular weight-adiponectin in patients with colorectal cancer: Association with chemotherapy and common genetic polymorphisms.

Colorectal cancer (CRC) is the third most frequently diagnosed cancer worldwide. Leptin and adiponectin are hormones produced by adipose tissues, which exhibit opposing effects on tumor growth. Leptin promotes tumor development and metastasis, whereas adiponectin attenuates this.

The Influence of Gene Polymorphisms on Infection and Triple Treatment Response Among Jordanian Population.

Background: () is considered the main cause of gastritis, peptic ulcer and gastric carcinoma in the human populations. infection influences the secretion level of several proinflammatory cytokines including IL-1β, which encoded by the gene.

Objective: The current study aimed to investigate whether gene polymorphisms are associated with infection among the Jordanian population and responses to triple therapy.

The Association between C1236T/C3435T SNPs and Infection among Jordanians.

Infection with () is very common and affecting about 50% of the worldwide population. Several genetic variations have been implicated in determining the clinical susceptibility to this infection. In the current study, we examined the association between C1236T (rs1045642) and C3435T (rs1045642) single nucleotide polymorphisms (SNPs) in the gene and the prevalence of infection among Jordanians.

Association of a New Germline Variant in the MUTYH DNA Glycosylase Gene with Colorectal Adenoma Transformation into Malignancy.

Background: MUTYH DNA glycosylase germline mutations are linked to the recessive inheritance of multiple adenoma. Studies have revealed that germline mutations in this gene are ethnicity related. This study aimed to identify the germline mutations in MUTYH gene and determine their prevalence among Jordanian patients with colorectal adenoma.

GRP78 regulates sensitivity of human colorectal cancer cells to DNA targeting agents.

This study was carried out to investigate the activation status of unfolded protein response (UPR) in colorectal cancer (CRC) and its contribution to CRC resistance to chemotherapy-induced apoptosis. Chemotherapy-induced apoptosis was assessed by the propidium iodide method. Activation of UPR was evaluated in CRC cell lines using immunoblotting technique and in CRC tissues using immunohistochemistry.

Does bicarbonate prevent contrast-induced nephropathy in cardiovascular patients undergoing contrast imaging?

A best evidence topic in cardiovascular surgery was written according to a structured protocol. The question addressed was whether administering sodium bicarbonate (NaHCO3) prevents contrast-induced nephropathy (CIN) in cardiovascular patients undergoing contrast imaging. In total, 266 papers were found using the reported search, 16 of which represented the best evidence to answer the clinical question.

Laparoscopic cholecystectomy in the elderly and young: a comparative study.

Background/aims: To assess the safety and effectiveness of simple laparoscopic cholecystectomy in the elderly patients and to compare it with that in younger patients.

Methodology: All patients underwent laparoscopic cholecystectomy in a four year period in a university hospital were retrospectively studied. They were divided in two groups according to the age: group A (65 years and above) and group B (below 65 years).

Prevalence of depression among relatives of cancer patients in Jordan: a cross-sectional survey.

Objective: Depression is common among chronically ill patients and their relatives. In this article, we investigated the prevalence of depression among relatives of cancer patients in Jordan, and studied the relation between several socio-demographic, disease- and treatment-related factors, together with the occurrence of depression among those relatives.

Method: A cross-sectional survey study was conducted at a major university hospital in Jordan.

Spontaneous regression in alveolar soft part sarcoma: case report and literature review.

Background: Sarcomas are a type of malignant tumors that arise from connective tissue. They are most of the time found in extremities

Case Presentation: We are presenting a case of adult male patient, who was found to have huge abdominal mass and multiple gastric and duodenal polyps. Pathological diagnosis for all lesions was Alveolar soft part sarcoma.