Association of gene common sequence variants in Jordanian patients with exfoliation syndrome and exfoliative glaucoma.

Aim: To investigate the association between single nucleotide polymorphisms (SNPs) in the gene with exfoliation syndrome/glaucoma (XFS/XFG) among Jordanians.

Methods: Sixty-one patients with XFS/XFG and 59 healthy control individuals were recruited in the study. Patients were diagnosed with XFS/XFG using standard clinical examination techniques.

Management outcome(s) in eyes with retinoblastoma previously inadequately treated with systemic chemotherapy alone without focal therapy.

Objective: The objective of this study was to evaluate the outcome of management in eyes with intraocular retinoblastoma (RB) that had received inadequate initial therapy (chemotherapy without focal therapy) before eventually receiving necessary consolidation therapy at a tertiary referral center.

Methods: A retrospective observational case series of 30 eyes from 26 RB patients who had initially received systemic chemotherapy as a sole therapy. The main outcome measures were demographics, laterality, International Classification of RB (ICRB), treatments, tumor control, and survival.

Surgical repair of rhegmatogenous retinal detachment in eyes harboring active retinoblastoma.

Background: Intraocular surgeries are classically contraindicated for patients with active Retinoblastoma (RB) due to the risk of tumor dissemination. Unfortunately, RB treatment may be complicated by rhegmatogenous retinal detachment (RD) that necessitates surgical repair especially in a child who is monocular from enucleation of the contralateral eye.

Objective: To assess the outcome of surgical repair of rhegmatogenous RD in children with RB using non-drainage scleral buckling.