Publications by authors named "Mohammed Asif Hussein"

Introduction Dopamine serves an essential function as a neurotransmitter, influencing the regulation of movement, cognitive processes, and emotional states. The identification of abnormal dopamine levels is critical for clinical diagnoses and scientific research, given its links to various disorders, including depression, schizophrenia, and Parkinson's disease. The distinctive electrochemical characteristics, stability, and broad bandgap of zinc sulfide (ZnS) nanostructures render them particularly fascinating.

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Article Synopsis
  • - The study focuses on synthesizing manganese(III) oxide (MnO), characterizing its structure, and analyzing its electrochemical properties, particularly in relation to dopamine detection, which is significant for medical diagnostics.
  • - MnO is synthesized using manganese sulfate and potassium permanganate in deionized water, followed by a series of heating and drying processes in a sealed autoclave to form hierarchical rod-like structures.
  • - Characterization techniques such as X-ray diffraction (XRD) and field emission scanning electron microscopy (FE-SEM) confirm the crystalline structure and 100 nm particle size of MnO, while cyclic voltammetry tests indicate improved sensing ability of the modified electrode compared to a bare electrode.
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Background  The article delineates a strategy for detecting ascorbic acid (AA) through the use of iron oxide (Fe₂O₃) nanoparticles on an electrode. The Fe₂O₃ nanoparticles demonstrated effective electrocatalysis in the oxidation of AA, resulting in increased peak currents. The sensor showcased a wide linear detection range, a low detection limit, and high selectivity towards interferents, making it suitable for accurate AA measurement in food analysis and medical diagnostics applications.

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  • - This study investigates the anti-metastatic effects of a flowering plant known as wild heliotrope on MCF-7 breast cancer cells, focusing on its ability to disrupt key signaling pathways.
  • - Using an MTT assay, the research found that the plant extract significantly inhibited cell growth, with maximum inhibition observed at a concentration of 150 μg/mL, and it suppressed important pathways like GSK3β and Wnt2.
  • - The findings suggest that the plant may serve as a potential anticancer agent against breast cancer, indicating further evaluation could be beneficial for different breast cancer types and cell lines.
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Background Electrochemical sensing is a versatile field that uses electrochemistry concepts to detect and measure various substances. It finds applications in clinical diagnostics and environmental monitoring. Scientists are currently working on creating reliable electrochemical sensing devices that can accurately detect ascorbic acid.

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Background This study investigates 's curative effectiveness against colon cancer cells. , often known as Elika jemudu, is a Convolvulaceae family plant. The inhibitory ability of anticancer herbal extracts against cancer cell growth and mediators is tested.

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Background:  An assessment of extract's antimicrobial and antioxidant properties was undertaken in light of its possible application as an oral care product. The maintenance of optimal dental health is just as important as overall wellness. Food particles become trapped in the mouth cavity, making it easy for oral bacteria to infect.

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Synopsis of recent research by authors named "Mohammed Asif Hussein"

  • Mohammed Asif Hussein's recent research primarily focuses on the synthesis and application of various nanoparticles and plant extracts for medical diagnostics and cancer treatment, highlighting their electrochemical properties and biological effects.
  • Key findings include the effective use of manganese(III) oxide for dopamine detection and iron oxide nanoparticles for the electrochemical detection of ascorbic acid, demonstrating their potential for diagnostic tools in clinical settings.
  • Additionally, his studies reveal promising anti-cancer properties of plant extracts such as Heliotropium bacciferum and Merremia emarginata, suggesting a potential for developing novel therapeutic strategies against breast and colon cancer.