Electrochemical water treatment: Review of different approaches.

The continued development in agriculture, the rapid growth of industrialization, and last but not least, the increase in the global population adversely affects the environment. The availability of drinking water decreases every year with the rise in water pollution, which is the consequence of the failure of conventional approaches to the water treatment process. This review will provide a comprehensive and detailed analysis of the electrochemical water treatment processes, as these techniques have several benefits over conventional methods, such as being cost-effective, easily applicable, selective, and broad applicability.

Impacts of microplastic accumulation in aquatic environment: Physiological, eco-toxicological, immunological, and neurotoxic effects.

The presence of microplastics (MPs) in aquatic ecosystem has become a pressing global concern. MPs pose a significant threat to aquatic ecosystems, with devastating consequences for both aquatic life and human health. Notably, freshwater ecosystems are particularly vulnerable to MPs pollution.

The Prevalence and Severity of Computer Vision Syndrome Among Primary Care Health Workers in the Ministry of National Guard Health Affairs, Central Region, Saudi Arabia.

Background Computer vision syndrome (CVS) is a common condition affecting individuals who spend prolonged periods using electronic devices. It is characterized by symptoms such as eye strain, dryness, headaches, and neck pain. This study aims to assess the prevalence of CVS symptoms among healthcare professionals, their awareness of the condition, and the effectiveness of various preventative practices.

Impact of Altitude on Erythrocyte Sedimentation Rate: A Cross-Sectional Study Using National Laboratory Data from Saudi Arabia.

Background: The erythrocyte sedimentation rate (ESR) is a widely used haematological test that indirectly measures inflammation in the body. It is influenced by various factors, including age, sex, and physiological condition. Altitude is another critical factor due to its impact on red blood cell physiology and plasma protein composition.

Nanoscale Systems for Local Activation of Hypoxia-Inducible Factor-1 Alpha: A New Approach in Diabetic Wound Management.

Chronic wounds in diabetic patients experience significant clinical challenges due to compromised healing processes. Hypoxia-inducible factor-1 alpha (HIF-1α) is a critical regulator in the cellular response to hypoxia, enhancing angiogenesis and tissue restoration. Nevertheless, the cellular response to the developed chronic hypoxia within diabetes is impaired, likely due to the destabilization of HIF-1α via degradation by prolyl hydroxylase domain (PHD) enzymes.

Fibrin scaffold encapsulated with epigallocatechin gallate microspheres promote neural regeneration and motor function recovery after traumatic spinal cord injury in rats.

Traumatic spinal cord injury (TSCI) is a serious medical issue where there is a loss of sensorimotor function. Current interventions continue to lack the ability to successfully enhance these conditions, therefore, it is crucial to consider alternative effective strategies. Currently, we investigated the effects of fibrin scaffold encapsulated with epigallocatechin gallate (EGCG) microspheres in the recovery of SCI in rats.

Tracing sources-oriented ecological risks of metal(loid)s in sediments of anthropogenically-affected coastal ecosystem from northeast bay of Bengal.

The current study focused on thirty-nine locations in the four islands (i.e., St.

Positive cystic duct margin for low grade dysplasia with intestinal metaplasia after routine laparoscopic cholecystectomy: Case report.

Introduction: Incidental neoplastic findings after routine cholecystectomy are becoming more common. However, low-grade dysplasia at the cystic duct resection margin remains rare and lacks established management guidelines.

Case Presentation: A 37-year-old male underwent a routine laparoscopic cholecystectomy.

Effect of Glycated Haemoglobin (HBA1c) on Cardiorespiratory Fitness (CRF) in a Population with Type 2 Diabetes Mellitus (T2DM): A Cross-Sectional Study.

The aim of this study was to evaluate cardiorespiratory fitness (CRF) measures, maximal oxygen consumption (VO max), and minute ventilation/carbon dioxide production (V/VCO slope and others) among the T2DM population based on glycated haemoglobin (HBA1c). The present study comprised a cross-sectional design, with two groups, based on HbA1c values (≤7 and ≥7.1).

Revolutionizing human healthcare with wearable sensors for monitoring human strain.

With the rapid advancements in wearable sensor technology, healthcare is witnessing a transformative shift towards personalized and continuous monitoring. Wearable sensors designed for tracking human strain offer promising applications in rehabilitation, athletic performance, occupational health, and early disease detection. Recent advancements in the field have centered on the design optimization and miniaturization of wearable biosensors.

Resveratrol: A Natural Compound Targeting the PI3K/Akt/mTOR Pathway in Neurological Diseases.

Neurological diseases (NDs), including neurodegenerative disorders and acute injuries, are a significant global health concern. The PI3K/Akt/mTOR pathway, a crucial signaling cascade, is responsible for the survival of cells, proliferation, and metabolism. Dysregulation of this pathway has been linked to neurological conditions, indicating its potential as a vital target for therapeutic approaches.

PU-H71 (NSC 750424): a molecular masterpiece that targets HSP90 in cancer and beyond.

Heat shock protein 90 (HSP90) is a pivotal molecular chaperone with multifaceted roles in cellular health and disease. Herein, we explore how HSP90 orchestrates cellular stress responses, particularly through its partnership with heat shock factor 1 (HSF-1). PU-H71, a selective inhibitor of HSP90, demonstrates significant potential in cancer therapy by targeting a wide array of oncogenic pathways.

Carotenoids as modulators of the PI3K/Akt/mTOR pathway: innovative strategies in cancer therapy.

Cancer progression is primarily driven by the uncontrolled activation of cellular signaling pathways, with the PI3K/Akt/mTOR (PAMT) pathway playing a central role. This pathway significantly contributes to the proliferation and survival of cancer cells, and its hyperactivity is a major challenge in managing several types of malignancies. This article delves into the promising potential of carotenoids, natural pigments found in abundance in fruits and vegetables, as a novel therapeutic strategy for cancer treatment.

Cellular stress response and neuroprotection of flavonoids in neurodegenerative diseases: Clinical insights into targeted therapy and molecular signaling pathways.

Neurodegenerative diseases (NDs) are caused by the gradual decline of neuronal structure and function, which presents significant challenges in treatment. Cellular stress responses significantly impact the pathophysiology of these disorders, often exacerbating neuronal damage. Plant-derived flavonoids have demonstrated potential as neuroprotective agents due to their potent anti-inflammatory, anti-apoptotic, and antioxidant properties.

Video Game-Based Trunk Exercises for Rehabilitation in Chronic Stroke Survivors: A Mixed-Methods Feasibility Study.

To assess the feasibility of video game-based trunk exercises using the Valedo system in a chronic stroke population. Ten chronic stroke survivors (eight males and two females, mean age 63 ± 15 years) were asked to complete 18 intervention sessions, each lasting 45 min., over 6-8 weeks.

BOLA family genes are the drivers and potential biomarkers of survival in kidney renal clear cell carcinoma patients.

Objectives: To analyze the diagnostic and prognostic potential of the BOLA gene family in kidney renal clear cell carcinoma (KIRC).

Methods: This study is an observational study. The whole study was carried out at Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia from January to November 2023.

Deciphering the importance of nanoencapsulation to improve the availability of bioactive molecules in food sources to the human body.

Various bodily functions are maintained, and health benefits are provided by food-derived bioactive components. Fruits and vegetables contain numerous beneficial components, including vitamins, minerals, antioxidants, enzymes, and phytonutrients. However, the body's ability to absorb these substances at a given rate and degree frequently limits their bioavailability.

The Efficacy and Safety of Inclisiran for Low-Density Lipoprotein (LDL) in Patients With Atherosclerotic Cardiovascular Disease (ASCVD): A Systematic Review of Randomized Controlled Trials.

This systematic review synthesizes current evidence to evaluate the safety and efficacy of inclisiran for lowering low-density lipoprotein cholesterol (LDL-C). A thorough search was conducted across four main databases - PubMed, Web of Science, SCOPUS, and Science Direct - for relevant studies published in the literature within the last five years (2020-2024). We included seven studies with a total of 6831 participants, of which 4661 (68.

Developing a machine learning model with enhanced performance for predicting COVID-19 from patients presenting to the emergency room with acute respiratory symptoms.

Artificial Intelligence is playing a crucial role in healthcare by enhancing decision-making and data analysis, particularly during the COVID-19 pandemic. This virus affects individuals across all age groups, but its impact is more severe on the elderly and those with underlying health issues like chronic diseases. This study aimed to develop a machine learning model to improve the prediction of COVID-19 in patients with acute respiratory symptoms.

Polyphenols in wound healing: unlocking prospects with clinical applications.

Wound healing is a multifaceted, complex process that factors like aging, metabolic diseases, and infections may influence. The potentiality of polyphenols, natural compounds, has shown anti-inflammatory and antimicrobial properties in promoting wound healing and their potential applications in wound management. The studies reviewed indicate that polyphenols have multiple mechanisms that promote wound healing.