A new two-parameter mixture family of generalized distributions: Statistical properties and application.

This paper introduces a novel two-parameter G-family of distributions derived through a mixing approach, where a mixture of the exponentiated G-family with parameter follows gamma distribution. Within this new family, we focus on the mixture of gamma-exponentiated exponential distribution (MGExED) as a key sub-model. The study thoroughly investigates by determining some of the MGExED statistical properties, such as quantile function, moments, and order statistics.

Knowledge, Awareness, and Attitudes Regarding Self-Medication With Non-opioid Analgesics Among Students in Hafar Al-Batin, Saudi Arabia: A Cross-Sectional Study.

Introduction: Self-medication (SM) with non-opioid analgesics (NOAs) has become increasingly prevalent, with individuals using over-the-counter medications to manage pain and other symptoms without professional guidance. While NOAs are generally considered safe when used appropriately, misuse or overuse can lead to adverse effects, including gastrointestinal issues, liver damage, and renal problems.

Aim: This study aimed to evaluate the knowledge, awareness, and attitudes regarding NOAs and their SM practices, including how these factors vary by demographic characteristics.

Prevalence of hyperlipidemia in psoriatic arthritis patients in Riyadh, Saudi Arabia.

Objectives: To estimate the prevalence of hyperlipidemia in patients with psoriatic arthritis (PsA) in Riyadh, Saudi Arabia, and to investigate the relationship between PsA and hyperlipidemia.

Methods: This retrospective study examined medical records of PsA patients from January 2010 to May 2023 at 2 medical centers in Riyadh. Patients over 18 years old with a lipid profile were included.

The impact of new VAT enforcement on financial performance: Evidence from Saudi Arabia non-financial listed companies using the event study and ARMA model.

This paper examines the influence of the new 15 % Value Added Tax (VAT) enforcement on non-financial listed companies in Saudi Arabia. By comparing financial data from 2019, before the VAT implementation and the COVID-19 pandemic, with data from 2020, during both the VAT increase and the pandemic, the research aims to uncover the consequences of this tax policy change. Utilizing charts, tables, and an event study analysis approach with the Autoregressive Moving Average (ARMA) model, we investigated key financial indicators such as Shareholders' Equity (SE), Total Income (TI), Total Revenues (TR), Net Income (NI), Total Expenses (TE), Other Changes in Operating Activity (COA), and Cash at the End of the Period (CEP).

Toe Walking Secondary to Tethered Spinal Cord Caused by Ganglioneuroma: A Case Report.

Toe walking is described by the incapacity to achieve heel strike during the stance phase of the gait cycle. When a child presents with toe walking beyond three years of age, a thorough evaluation is crucial. We report a case of a seven-year-old female presented with painless toe walking that started two years prior to presentation.

Influence of Oral Habits on Pediatric Malocclusion: Etiology and Preventive Approaches.

Teeth malocclusion refers to the misalignment of teeth and improper occlusion of the upper and lower jaws when the mouth is closed, which can lead to both aesthetic and functional issues such as difficulties with chewing, biting, and speech. These challenges may further contribute to broader health concerns. One of the major contributing factors to malocclusion in children is the presence of certain oral habits.

Integrating Computational Modeling and Experimental Validation to Unveil Tyrosinase Inhibition Mechanisms of Flavonoids from .

Flavonoids, natural compounds ubiquitous in the human diet, are esteemed for their multifaceted pharmacological properties. The tyrosinase inhibitory capacity of five flavonoids from was investigated through a comprehensive integration of and methodologies. Molecular docking simulations demonstrated the proficient binding of the isolated compounds to the principal binding site of tyrosinase, akin to the standard tyrosinase inhibitor kojic acid.

Association Between Serum Vitamin D Level and Uncontrolled Chronic Rhinosinusitis With Nasal Polyposis.

Chronic rhinosinusitis with nasal polyposis (CRSwNP) is characterized by type 2 inflammation, and studies have shown that conventional therapy usually yields unsatisfactory results. While recent studies have indicated the potential effect of vitamin D on allergic and inflammatory diseases, including CRSwNP. Therefore, this study aimed to investigate the relationship between serum vitamin D levels and the severity of CRSwNP using endoscopic evaluations, imaging, patient-reported outcome measures, absolute eosinophilic count, and serum vitamin D levels and determine the prevalence of vitamin D deficiency in patients with CRSwNP.

Constructing ZnO/NiO Nanocomposites as a Photocatalyst and Investigating Photocatalytic Effectiveness for Wastewater Treatment.

The goal of the present work is to create ZnO/NiO nanocomposites (NCs) for the photocatalytic destruction of organic contaminants using the co-precipitation technique. To investigate physiochemical characteristics, FT-IR, UV visible spectroscopy, SEM, and XRD were used. The ZnO hexagonal phase and the NiO cubic phase in the ZnO/NiO NCs were verified by the diffraction pattern.

Diallyl disulfide prevents cadmium-induced testicular injury by attenuating oxidative stress, apoptosis, and TLR-4/NF-κB and JAK1/STAT3 signaling and upregulating SIRT1 in rats.

Background: Cadmium (Cd) is a heavy metal environmental pollutant that can cause serious health problems. Cd can cause structural changes in the testes and exposure to this heavy metal is associated with the loss of sperms and male infertility. The role of oxidative stress and inflammation in Cd toxicity has been acknowledged.

Molecular engineering on tyrian puprle natural dye as TiO based fined tuned photovoltaic dye material: DFT molecular analysis.

In this research, molecular modification is employed to see the enhancement in the efficiency of Tyrian Purple (TP), a natural dye, for organic photovoltaic materials. By using Density Functional Theory (DFT) based molecular modeling, seven new structures are designed with pi spacer to extend electron donor moieties. Teheir Frontier Molecular Orbital (FMO) analysis demonstartes their charges with a similar pattern of distributions over their Highest Occupied and Lowed Unocuupied Molecular Orbitals (HOMO/lUMO).

Diallyl Disulfide Mitigates Cadmium Hepatotoxicity by Attenuating Oxidative Stress and TLR-4/NF-κB Signaling and Upregulating PPARγ.

Background: Heavy metals can cause serious health problems that affect different organs. Cadmium (Cd) is an environmental contaminant known for its toxicological consequences on different organs. Hepatotoxicity is a serious effect of exposure to Cd with oxidative stress (OS) and inflammation playing a central role.

Locally Synthesized Zwitterionic Surfactants as EOR Chemicals in Sandstone and Carbonate.

Zwitterionic surfactants are found to be highly effective in reducing the IFT and changing the wettability. This work studied the solubility and wettability alteration performance of locally synthesized zwitterionic surfactants in Berea sandstone and Indiana limestone. Contact angle measurements were conducted to study the wettability under different conditions.

Adult Simultaneous Cochlear Implantation: Local Anesthesia.

: Cochlear implant (CI) surgery is conventionally done under general anesthesia (GA). However, many patients are unable to undergo GA due to various reasons, raising the need for an alternative safe option. CI under local anesthesia is feasible and safely done in patients who can't tolerate GA.

The Investigation of Structural, Optical and Thermal Properties of Nickel Doped CeO Integrated PVC Nanocomposite.

PVC nanocomposite (NC) films with cubic CeO and Ni-doped CeO (NDC) have been prepared using a conventional solution-casting technique. The prepared films were characterized with FT-IR spectrometer, X-ray diffraction (XRD), and scanning electron microscopy (SEM). The optical and thermal properties of the films were evaluated using a UV-visible spectrophotometer and TGA/DSC.

Expression of concern: A well-defined S-g-CN/Cu-NiS heterojunction interface towards enhanced spatial charge separation with excellent photocatalytic ability: synergetic effect, kinetics, antibacterial activity, and mechanism insights.

Expression of concern for 'A well-defined S-g-CN/Cu-NiS heterojunction interface towards enhanced spatial charge separation with excellent photocatalytic ability: synergetic effect, kinetics, antibacterial activity, and mechanism insights' by Haya A. Abubshait , , 2022, , 3274-3286, https://doi.org/10.

Photothermal effectiveness of microporous carbon nanospheres incorporated with polysulfone in direct contact membrane distillation.

Carbon nano-spheres (CNS) were synthesized a hydrothermal method using d-glucose as a precursor, followed by pyrolysis in a nitrogen atmosphere. The resulting CNS were integrated into polysulfone (PSF) membranes to enhance their photothermal properties. Characterization using various techniques revealed improved thermal properties upon CNS inclusion, with a notable increase in membrane surface temperature and enhancement of contact angle (CA) and liquid entry pressure (LEP).

Modulating Decarboxylative Oxidation Photocatalysis by Ligand Engineering of Atomically Precise Copper Nanoclusters.

Copper nanoclusters (Cu NCs) characterized by their well-defined electronic and optical properties are an ideal platform for organic photocatalysis and exploring atomic-level behaviors. However, their potential as greener, efficient catalysts for challenging reactions like decarboxylative oxygenation under mild conditions remains unexplored. Herein, we present Cu(Nap)(PPh)H (hereafter CuNap), protected by 1-naphthalene thiolate (Nap), which performs well in decarboxylative oxidation (90% yield) under photochemical conditions.

Screening of overactive bladder syndrome and its relation with insomnia: A public health experience.

Background: Overactive bladder (OAB) syndromes are a vital global issue linked to sleep disturbances and insomnia. This survey explores the relationship between these health burden issues and their risk factors.

Methodology: A survey-based study was conducted among Makkah city citizens' in April 2023.

Galangin attenuates chlorpyrifos-induced kidney injury by mitigating oxidative stress and inflammation and upregulating Nrf2 and farnesoid-X-receptor in rats.

Chlorpyrifos (CPF) is a highly toxic commonly used pesticide and can seriously harm human health. This study assessed the potential of galangin (GAL), an antioxidant flavonoid, to attenuate oxidative stress, inflammation and kidney injury caused by CPF, emphasizing the role of farnesoid-x-receptor (FXR) and Nrf2. Rats were supplemented with CPF and GAL for 28 days.

Nephrectomies in Saudi Arabia: A Comprehensive Analysis of Outcomes from a High-Volume Minimally Invasive Surgery Center.

Literature reporting on the outcomes of the different procedures of nephrectomies (open vs laparoscopic vs robotic) in Saudi Arabia remains limited. Compare surgical and oncological outcomes between open and minimally invasive nephrectomies. A retrospective cohort study.