Publications by authors named "Mohammed Ali Alodat"

Background: ICU readmission is associated with poor outcomes. Few studies have directly compared the outcomes of early versus late readmissions, especially in Saudi Arabia.

Objective: To compare the outcomes between early and late ICU readmissions, mainly with regards to hospital mortality.

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Article Synopsis
  • The ISARIC mortality score is a tool designed to predict the risk of in-hospital death among COVID-19 patients, primarily validated on a British population, prompting the need for testing its effectiveness in other regions.
  • This study focused on external validation of the ISARIC score in a large ICU in Saudi Arabia, analyzing data from 1493 adult COVID-19 patients admitted between March 2020 and June 2021.
  • Results indicated that the ISARIC score effectively predicted mortality, with a cutoff value of >9 showing 70.5% sensitivity and 73.97% specificity, establishing its reliability for critically ill COVID-19 patients in the Saudi cohort.
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Background: Sepsis and septic shock are major causes of morbidity and mortality worldwide, associated with a high economic and social burden on healthcare systems and communities, yet with few definite treatment modalities. The efficacy of steroids in the management of sepsis or septic shock remains a controversy and subject of investigation due to their theoretical beneficial effects.

Methods: This was a systematic literature review and meta-analysis on randomized controlled trials of hydrocortisone usage in sepsis or septic shock as of 2000, following the GRADE methodology, considering a primary outcome of 28 day all-cause mortality.

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