Publications by authors named "Mohammed AlSaeedy"

The present work was designed to synthesize AgO-supported MgO/rGO nanocomposites (NCs) via green method using Phoenix leaf extract for improved photocatalytic and anticancer activity. Green synthesized AgO-supported MgO/rGO NCs were characterized through X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), X-ray photoelectron spectroscopy (XPS), Raman, ultraviolet-visible (UV-vis) spectroscopy, and photoluminescence (PL) spectroscopy, and gas chromatography-mass spectroscopy (GC-MS) was applied to examine the chemical components of the Phoenix leaf extract. Characterization data confirmed the preparation of MgO NPs, AgO-MgO NCs, and AgO-MgO/rGO NC with particle size of 26-28 nm.

View Article and Find Full Text PDF

In order to address the challenges associated with antibiotic resistance by bacteria, two new complexes, Ni(II) and Zn(II), have been synthesized using the conventional method based on Schiff base ligand (E)-2-((5-bromothiazol-2-yl) imino) methyl) phenol. The Schiff base ligand (HL) was synthesized using salicylaldehyde and 5-(4-bromophenyl)thiazol-2-amine in both traditional and efficient, ecologically friendly, microwave-assisted procedures. The ligand and its complexes were evaluated by elemental analyses, FTIR spectroscopy, UV-Vis spectroscopy, nuclear magnetic resonance (NMR), thermogravimetric analysis (TGA) and magnetic susceptibility.

View Article and Find Full Text PDF

This investigation delves into the potential use of halogen bonding to enhance both the short-circuit current () and overall efficiency of dye-sensitized solar cells (DSSCs). Specifically, we synthesized two distinct dyes, SQI-F and SQI-Cl, and characterized them using FT-IR, HNMR, C NMR, and mass spectroscopy. These dyes are based on the concept of incorporating halogen atoms within unsymmetrical squaraine structures with a donor-acceptor-donor (D-A-D) configuration.

View Article and Find Full Text PDF
Article Synopsis
  • A series of novel 1,2,3-triazole and 1,2,3-triazoline glycosides were synthesized from d-arabinose to create hybrid molecules featuring sugar azide, with key steps involving the protection of hydroxyl groups and introduction of ethylene glycol.
  • The synthesis of azido ethyl-O-β-d-arabinofuranoside was achieved using sodium azide to replace a tosylate group, followed by a 1,3-dipolar cycloaddition reaction with various alkenes and alkynes to create new glycosides.
  • Characterization through various analytical techniques confirmed moderate to high antimicrobial activity against test microorganisms, alongside promising pharmacokinetic properties, with molecular docking analysis
View Article and Find Full Text PDF
Article Synopsis
  • A new series of mono-5-isoxazolidines and bis (5-isoxazolidines) was synthesized through a specific chemical reaction aimed at developing new antimicrobial and antioxidant drugs.
  • The compounds were fully characterized using advanced techniques like FT-IR and NMR spectroscopy, and their physicochemical and pharmacokinetic properties were predicted using computational methods.
  • Many of the synthesized compounds demonstrated significant antimicrobial and antifungal activity, outperforming standard drugs in some cases, with varying levels of antioxidant properties revealed through further testing and molecular docking studies.
View Article and Find Full Text PDF

A systematic literature survey published in several journals of pharmaceutical chemistry and of chromatography used to analyze impurities for most of the drugs that have been reviewed. This article covers the period from 2016 to 2020, in which almost of chromatographic techniques have been used for drug impurity analysis. These chromatography techniques are important in the analysis and description of drug impurities.

View Article and Find Full Text PDF