Autonomous Large-Scale Radon Mapping and Buoyant Plume Modeling Quantify Deep Submarine Groundwater Discharge: A Novel Approach Based on a Self-Sufficient Open Ocean Vehicle.

Groundwater discharge into the sea occurs along many coastlines around the world in different geological settings and constitutes an important component of global water and matter budget. Estimates of how much water flows into the sea worldwide vary widely and are largely based on onshore studies and hydrological or hydrogeological modeling. In this study, we propose an approach to quantify a deep submarine groundwater outflow from the seafloor by using autonomously measured ocean surface data, i.

Semiconstrained posterior-stabilized total knee arthroplasty: indications, risks and benefits in primary and revision surgery.

Background: The constrained posterior-stabilized (CPS) implant for use in total knee arthroplasty (TKA) has a constraint level midway between that of a posterior-stabilized implant and a valgus-varus-constrained implant; there is currently no consensus on the surgical indications for use of this degree of constraint. We present our experience using this implant at our centre.

Methods: We reviewed the charts of patients who received a CPS polyethylene insert during TKA in our centre between January 2016 and April 2020.

Erratum: Orofacial overgrowth with peripheral nerve enlargement and perineuriomatous pseudo-onion bulb proliferations is part of the -related overgrowth spectrum.

[This corrects the article DOI: 10.1016/j.xhgg.

Assessment of the effect of silica calcium phosphate nanocomposite on mesenchymal stromal cell differentiation and bone regeneration in critical size defect.

Objective: The research was designed to assess silica calcium phosphate nanocomposite (SCPC) biocompatibility and bioactivity as an osteoinductive scaffold and cell carrier. Consequently, the ability of cell seeded SCPC implant to regenerate a critical size defect in rat calvarium.

Materials And Methods: The study was conducted in two parts.

Substrate Protection with Corrosion Scales: Can We Depend on Iron Carbonate?

Controlling corrosion with naturally occurring corrosion scales is potentially a more environmentally sustainable alternative to current approaches, including dosing of organic corrosion inhibitors. We report grazing incidence X-ray diffractograms correlated with electrochemical measurements to elucidate the growth and corrosion protection properties of a corrosion scale composed of FeCO crystallites, which is encountered in various key energy industry applications. Data, acquired as a function of time from high-purity iron immersed in CO-saturated deionized HO at pH 6.

Evaluation of the regenerative potential of decellularized skeletal muscle seeded with mesenchymal stromal cells in critical-sized bone defect of rat models.

Background: The morbidities and complications reported in the reconstruction of large bony defects have inspired progression in the field of bioengineering, with a recent breakthrough for the use of decellularized skeletal muscle grafts (DSMG).

Aim: To assess the osteogenic potentials of seeded DSMG and to investigate bone regeneration in critical size defect

Materials And Methods: Assessment of cell viability and characterization was carried out on seeded DSMG for different intervals . For experiments, histological analysis was performed for rat cranial defects for the following groups: (A) non-treated DSMG and (B) seeded DSMG after a period of 8 weeks.

Giant Parotid Pleomorphic Adenoma with Atypical Histological Presentation and Long-Term Recurrence-Free Follow-Up after Surgery: A Case Report and Review of the Literature.

Salivary gland tumors (SGT) comprise 3% of all head and neck tumors, are mostly benign, and arise frequently in the parotid gland. Pleomorphic adenoma (PA) is the commonest SGT, representing 60-70% of all benign parotid tumors. Clinically, parotid PA presents as irregular, lobulated, asymptomatic, slow-growing preauricular mass, involving both superficial and deep lobes, and could grow to gigantic proportions.

Orofacial overgrowth with peripheral nerve enlargement and perineuriomatous pseudo-onion bulb proliferations is part of the -related overgrowth spectrum.

Individuals with orofacial asymmetry due to mucosal overgrowths, ipsilateral bone and dental aberrations with perineurial hyperplasia and/or perineuriomatous pseudo-onion bulb proliferations, comprise a recognizable clinical entity. In this article, we describe three individuals with this clinical entity and mosaic variants c.3140A>G (p.

Clinical and Genetic Characteristics of Familial Hypercholesterolemia at Sultan Qaboos University Hospital in Oman.

Objectives: We sought to describe the clinical and genetic characteristics of patients with familial hypercholesterolemia (FH) that presented to the lipid clinic at Sultan Qaboos University Hospital, Muscat, Oman.

Methods: Patients who presented with high low-density lipoprotein cholesterol (LDL-C) levels (> 189.0 mg/dL or 4.

Peri-implant soft tissue status and crestal bone loss around immediately-loaded narrow-diameter implants placed in cigarette-smokers: 6-year follow-up results.

Background: It is hypothesized that in the long-term, soft tissue inflammation (reflected by increased scores of peri-implant probing-depth [PD]) and crestal bone loss (CBL) is higher in cigarette-smoker than nonsmokers with narrow diameter implants (NDIs).

Purpose: The aim of the present 6-years' follow-up clinical observational study was to compare the peri-implant soft tissue inflammatory parameters (plaque index [PI], gingival index [GI], and PD) and CBL around immediately-loaded NDIs placed in cigarette-smokers and nonsmokers.

Materials And Methods: In all groups, peri-implant GI, PI and PD were measured on six sites (distolingual/palatal, mesiolingual/palatal mesiobuccal, distobuccal, midlingual/palatal, and midbuccal) per implant.

In silico analysis of a novel causative mutation in Cadherin23 gene identified in an Omani family with hearing loss.

Background: Hereditary hearing loss is a heterogeneous group of complex disorders with an overall incidence of one in every 500 newborns presented as syndromic and non-syndromic forms. Cadherin-related 23 (CDH23) is one of the listed deafness causative genes. It is found to be expressed in the stereocilia of hair cells and in the retina photoreceptor cells.

Corrosion Protection through Naturally Occurring Films: New Insights from Iron Carbonate.

Despite intensive study over many years, the chemistry and physics of the atomic level mechanisms that govern corrosion are not fully understood. In particular, the occurrence and severity of highly localized metal degradation cannot currently be predicted and often cannot be rationalized in failure analysis. We report a first-principles model of the nature of protective iron carbonate films coupled with a detailed chemical and physical characterization of such a film in a carefully controlled environment.

Delayed Healing of Tooth Extraction Sockets After Vascular Endothelial Growth Factor Inhibition by Bevacizumab.

Purpose: This study aimed to explore the effect of the chemotherapeutic agent bevacizumab on the extraction socket healing process in New Zealand rabbits.

Materials And Methods: The animals received intraperitoneal bevacizumab treatment for 6 consecutive weeks (3 mg/kg per week). The right mandibular first premolar was extracted in the second week of the experiment, and the jaw bone containing the socket tissues was harvested at the end of the treatment period.

LHFPL5 mutation: A rare cause of non-syndromic autosomal recessive hearing loss.

Hearing loss is a debilitating disorder that impairs language acquisition, resulting in disability in children and potential isolation in adulthood. Its onset can have a genetic basis, though environmental factors, which are often preventable, can also cause the condition. The genetic forms are highly heterogeneous, and early detection is necessary to arrange appropriate patient support.

Undergraduate Implant Dentistry Training In Saudi Dental Schools.

Background: Implant dentistry training at the undergraduate level has been introduced only recently in Saudi dental schools and there is only limited data available about it. The objective of the present study was to evaluate the current status of undergraduate dental implant education in Saudi Dental Schools.

Methods: A two-part questionnaire-based study was conducted in Saudi university dental schools targeted towards undergraduate program directors to assess the quantity and quality of implant dentistry training being integrated into the curriculum.

A comprehensive study on microstructure and tensile behaviour of a selectively laser melted stainless steel.

316L stainless steel samples have been prepared by selective laser melting (SLM) using a pulsed laser mode and different laser powers and scanning patterns. The as-fabricated samples were found to be dominated by clusters of nano-sized γ needles or cells. TEM imaging shows that these needles contain a high population of dislocations while TEM-EDX analysis reveals high chemical homogeneity throughout the as-fabricated samples as evidenced by the fact that there is even no micro-/nano-segregation at interfaces between neighbouring γ needles.

Oral Kaposi Sarcoma in HIV-seronegative Saudi patient: Literature review and case report.

Kaposi Sarcoma (KS) is an intermediate neoplasm affecting the endothelial cells of mucous membranes and skin. It arises most commonly among HIV-infected individuals. We present an intra-oral KS in an 80-year-old Saudi male patient, who is HIV-seronegative, non-immunosuppressed, and with no history of organ transplantation.

A rare case of inflammatory myofibroblastic tumor of the mandible mimicking a malignant tumor.

Inflammatory myofibroblastic tumor (IMT) of the head and neck is a rare benign proliferative lesion of unknown etiology that mimics malignant lesions clinically and radiographically. I report the case of a 27-year-old woman who presented with a mass in her left mandible associated with restricted mouth opening that had developed over the preceding 7 months. The mass was resected completely with 5 mm margin under general anesthesia.

A novel missense mutation in the C2C domain of otoferlin causes profound hearing impairment in an Omani family with auditory neuropathy.

Objectives: To identify genetic defects in an Omani family diagnosed with deafness. 

Methods: A cross-sectional association study was conducted at the Department of Biochemistry, College of Medicine and Health Sciences, Sultan Qaboos University, Al-Khoud, Oman and the Centre of Medical Genetics, University of Antwerp, Antwerp, Belgium between August 2010 and September 2014. Microsatellites markers for nine non-syndromic genes were used to genotype the defective locus using the extracted DNA from family members.

Real-Time Assessment of Guided Bone Regeneration in Standardized Calvarial Defects in Rats Using Bio-Oss With and Without Collagen Membrane: An In Vivo Microcomputed Tomographic and Histologic Experiment.

In vivo microcomputed tomography (μCT) enables real-time assessment of bone regeneration. The aim of this μCT and histologic experiment was to assess guided bone regeneration (GBR) around standardized calvarial defects in rats using particulate graft material (Bio-Oss) with and without collagen membranes (CMs). Eighteen female Sprague-Dawley rats aged 6 weeks and weighing 300 g were used.

Efficacy of Mucograft vs Conventional Resorbable Collagen Membranes in Guided Bone Regeneration Around Standardized Calvarial Defects in Rats: An In Vivo Microcomputed Tomographic Analysis.

The aim of this in vivo microcomputed tomographic (μCT) study was to compare the efficacy of Mucograft (MG) vs resorbable collagen membranes (RCMs) in facilitating guided bone regeneration (GBR) around standardized calvarial defects in rats. Forty female Wistar albino rats with a mean age and weight of 6 to 9 weeks and 250 to 300 g, respectively, were used. With the rats under general anesthesia, the skin over the calvaria was exposed using a full-thickness flap.

A comparison study on the design of mirror and anatomy reconstruction technique in maxillofacial region.

Background: The customized mandible reconstruction has been a challenging task in maxillofacial surgery. Designing an implant taking into considering the surrounding bone contours is really critical. Various computer aided design techniques have been used in the designing the customized reconstruction implants, but nevertheless study on the comparison between these techniques is rarely used.

Hoxb13, a potential prognostic biomarker for prostate cancer.

HOXB13, a member of the homeobox proteins family, is a key regulator of the epithelial differentiation in the prostate gland. HOXB13 is overexpressed during malignant progression of the prostatic tissue and suspected to contribute in the pathogenesis of the prostate gland. In androgen deprived conditions, HOXB13 is thought to act through inhibition of the tumour suppressor protein p21.