Unveiling the therapeutic potential of leaves: Exploring antioxidant, anti-inflammatory, anti-arthritic, and cytotoxic activities through biological and molecular docking evaluation with DFT analysis.

Background: is a common tropical seacoast flowering plant from the family of Fabaceae which is reported as bay bean and coastal jack bean; has a wide range of therapeutic and nutraceutical properties.

Aim: The present research aims to explore some pharmacological insights of the methanol extract of leaves (MECR) and its chloroform fraction (CFCR) and n-hexane fraction (NFCR) through and approaches.

Methods: Different fractions of were subjected to ferric reduction assay and total phenolic and flavonoid content assay to explore their antioxidant potential.

Recent advances in the biosynthesis, bioavailability, toxicology, pharmacology, and controlled release of citrus neohesperidin.

Neohesperidin (hesperetin 7-O-neohesperidoside), a well-known flavanone glycoside widely found in citrus fruits, exhibits a variety of biological activities, with potential applications ranging from food ingredients to therapeutics. The purpose of this manuscript is to provide a comprehensive overview of the chemical, biosynthesis, and pharmacokinetics profiles of neohesperidin, as well as the therapeutic effects and mechanisms of neohesperidin against potential diseases. This literature review covers a wide range of pharmacological responses elicited by Neohesperidin, including neuroprotective, anti-inflammatory, antidiabetic, antimicrobial, and anticancer activities, with a focus on the mechanisms of those pharmacological responses.

Anxiolytic, antidepressant and antioxidant activity of the methanol extract of leaves.

Background And Aim: This study evaluated the anxiolytic, antidepressant, and antioxidant activity of the methanol extract of (MECR) leaves, and determined the total phenolic and flavonoid contents in this extract.

Experimental Procedure: The anxiolytic effect of MECR (100, 200, 400 mg/kg, p. o.

Chemical profiles and pharmacological insights of Anisomeles indica Kuntze: An experimental chemico-biological interaction.

Anisomeles indica (L.) Kuntze is an ethnomedicinally important plant that has long been used in traditional medicine to treat a variety of ailments, including dyspepsia, abdominal pain, colic, allergies, inflammation, and rheumatic arthritis. However, the scientific framework underlying these medicinal properties is not well known.

Antioxidant-Rich Leaf Extract Alleviates Depressive-Like Behaviors and Impede Hyperglycemia.

Dhaiphul () is a frequently demanded plant in South-East Asian regions for its diverse medicinal values. This study was proposed to examine antioxidant, antidiabetic, and antidepressant potentials of methanol extract of leaves (MEWF) and its derived n-hexane (NHFMEWF) and ethyl acetate (EAFMEWF) fractions through in vitro, in vivo, and computational models. Among test samples, MEWF and EAFMEWF contained the highest phenolic content and showed maximal antioxidant activity in DPPH radical scavenging and ferric reducing power assays.